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Personalised nutrit...
Personalised nutrition : status and perspectives
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Joost, Hans-Georg (author)
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Gibney, Michael J. (author)
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Cashman, Kevin D. (author)
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- Görman, Ulf (author)
- Lund University,Lunds universitet,Tros- och livsåskådningsvetenskap,Centrum för teologi och religionsvetenskap,Institutioner,Humanistiska och teologiska fakulteterna,Studies in Faith and World Views,Centre for Theology and Religious Studies,Departments,Joint Faculties of Humanities and Theology
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Hesketh, John E. (author)
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Mueller, Michael (author)
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van Ommen, Ben (author)
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Williams, Christine M. (author)
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Mathers, John C. (author)
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(creator_code:org_t)
- 2007
- 2007
- English.
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In: British Journal of Nutrition. - 1475-2662. ; 98:01, s. 26-31
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Personalised, genotype-based nutrition is a concept that links genotyping with specific nutritional advice in order to improve the prevention of nutrition-associated, chronic diseases. This review describes the current scientific basis of the concept and discusses its problems. There is convincing evidence that variant genes may indeed determine the biological response to nutrients. The effects of single-gene variants on risk or risk factor levels of a complex disease are, however, usually small and sometimes inconsistent. Thus, information on the effects of combinations of relevant gene variants appears to be required in order to improve the predictive precision of the genetic information. Furthermore, very few associations between genotype and response have been tested for causality in human intervention studies, and little is known about potential adverse effects of a genotype-derived intervention. These issues need to be addressed before genotyping can become an acceptable method to guide nutritional recommendations.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- disease risk
- genotype
- nutrigenetics
- nutritional recommendations
- nutrigenomics
Publication and Content Type
- for (subject category)
- ref (subject category)
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