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- Hindsén, MonicaLund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups (author)
Photoallergic contact dermatitis from ketoprofen induced by drug-contaminated personal objects
- Article/chapterEnglish2004
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- Elsevier BV,2004
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- LIBRIS-ID:oai:lup.lub.lu.se:c0b2c840-1960-452c-9111-1869f88857b5
- https://lup.lub.lu.se/record/899404URI
- https://doi.org/10.1016/j.jaad.2003.07.007DOI
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- Language:English
- Summary in:English
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- Background: Photoallergic contact dermatitis from ketoprofen has been recognized since the mid-1980s. Skin reactions have been reported to continue weeks after discontinuation of ketoprofen. One reason for this could be residual ketoprofen in the skin, which has been shown in a skin biopsy specimen. Objective: We sought to report on 3 cases of photoallergic contact dermatitis from ketoprofen in topical anti-inflammatory gels and on relapses of dermatitis appearing after use of ketoprofen-contaminated objects. Methods: We patch and photopatch tested, with standard series, the anti-inflammatory gel, ketoprofen, and its ingredients in serial dilutions and extracts of personal objects. We performed chemical investigations of personal objects with thin-layer chromatography, high-pressure liquid chromatography, and gas chromatography-mass spectrometry. Results: Photoallergy was demonstrated to ketoprofen, which was detected in personal objects. Conclusion: Relapses of photoallergic contact dermatitis in patients photoallergic to ketoprofen can be induced by ketoprofen-contaminated objects such as bandages and slippers.
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- Isaksson, MarléneLund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups(Swepub:lu)derm-mis (author)
- Persson, L (author)
- Zimersson, E (author)
- Bruze, MagnusLund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups(Swepub:lu)derm-mbr (author)
- Yrkes- och miljödermatologiForskargrupper vid Lunds universitet (creator_code:org_t)
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- In:Journal of American Academy of Dermatology: Elsevier BV50:2, s. 215-2190190-9622
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