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Extracellular Matrix Biomarker, Fibulin-1, Is Closely Related to NT-proBNP and Soluble Urokinase Plasminogen Activator Receptor in Patients with Aortic Valve Stenosis (The SEAS Study).

Kruger, Ruan (author)
Rasmussen, Lars M (author)
Argraves, William S (author)
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Eugen-Olsen, Jesper (author)
Nielsen, Olav W (author)
Blyme, Adam (author)
Willenheimer, Ronnie (author)
Lund University,Lunds universitet,Kardiologiska klinikens forskargrupp,Forskargrupper vid Lunds universitet,Cardiology Research Group,Lund University Research Groups
Wachtell, Kristian (author)
Olsen, Michael H (author)
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 (creator_code:org_t)
2014-07-11
2014
English.
In: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:7
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Fibulin-1, a circulating extracellular matrix glycoprotein, has been associated with arterial disease and elevated N-terminal prohormone B-type natriuretic peptide (NT-proBNP) in diabetes. Soluble urokinase plasminogen activator receptor (suPAR), a marker of inflammation, has been associated with subclinical atherosclerosis. Therefore, we aimed to explore the interplay between these biomarkers and mild to moderate aortic valve stenosis (AS).

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

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