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Who Still Gets Liga...
Who Still Gets Ligated? Reasons for Persistence of Surgical Ligation of the Patent Ductus Arteriosus Following Availability of Transcatheter Device Occlusion for Premature Neonates
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- Hoffmann, Julia K. (author)
- Boston Children's Hospital
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- Khazal, Zahra (author)
- Boston Children's Hospital
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- Apers, Wievineke (author)
- Boston Children's Hospital
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- Sharma, Puneet (author)
- Boston Children's Hospital
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- Weismann, Constance G. (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Barnkardiologi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Children cardiology,Lund University Research Groups,Skåne University Hospital,Ludwig-Maximilian University of Munich
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- Kaganov, Kira (author)
- Tel Aviv Sourasky Medical Center – Ichilov Hospital
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- Wheeler, Craig R. (author)
- Boston Children's Hospital
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- Farias, Michael (author)
- Boston Children's Hospital
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- Porras, Diego (author)
- Boston Children's Hospital
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- Levy, Philip (author)
- Boston Children's Hospital
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- Morton, Sarah U. (author)
- Boston Children's Hospital
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(creator_code:org_t)
- 2024
- 2024
- English.
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In: Journal of cardiovascular development and disease. - 2308-3425. ; 11:5
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- (1) Background: To identify reasons for the persistence of surgical ligation of the patent ductus arteriosus (PDA) in premature infants after the 2019 Food and Drug Administration (FDA) approval of transcatheter device closure; (2) Methods: We performed a 10-year (2014–2023) single-institution retrospective study of premature infants (<37 weeks) and compared clinical characteristics and neonatal morbidities between neonates that underwent surgical ligation before (epoch 1) and after (epoch 2) FDA approval of transcatheter closure; (3) Results: We identified 120 premature infants that underwent surgical ligation (n = 94 before, n = 26 after FDA approval). Unfavorable PDA morphology, active infection, and recent abdominal pathology were the most common reasons for surgical ligation over device occlusion in epoch 2. There were no differences in demographics, age at closure, or outcomes between infants who received surgical ligation in the two epochs; (4) Conclusions: Despite increasing trends for transcatheter PDA closure in premature infants, surgical ligation persists due to unfavorable ductal morphology, active infection, or abdominal pathology.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- patent ductus arteriosus
- PDA
- prematurity
- surgical ligation
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Hoffmann, Julia ...
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Khazal, Zahra
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Apers, Wievineke
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Sharma, Puneet
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Weismann, Consta ...
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Kaganov, Kira
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show more...
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Wheeler, Craig R ...
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Farias, Michael
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Porras, Diego
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Levy, Philip
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Morton, Sarah U.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
- Articles in the publication
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Journal of cardi ...
- By the university
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Lund University