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- JOHANSSON, BERTILLund University,Lunds universitet,Avdelningen för klinisk genetik,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Clinical Genetics,Department of Laboratory Medicine,Faculty of Medicine,Skåne University Hospital (author)
Normal frequency of structural chromosome aberrations in fibroblasts from patients with non‐Hodgkin's lymphoma
- Article/chapterEnglish1988
Publisher, publication year, extent ...
- 2008-02-14
- Springer Science and Business Media LLC,1988
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- LIBRIS-ID:oai:lup.lub.lu.se:c76ffa6d-89a4-4c4f-a5fe-a85225533726
- https://lup.lub.lu.se/record/c76ffa6d-89a4-4c4f-a5fe-a85225533726URI
- https://doi.org/10.1111/j.1601-5223.1988.tb00365.xDOI
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- Language:English
- Summary in:English
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- The incidence of chromosome aberrations, i.e., chromatid and chromosome gaps, breaks, and exchanges, was studied in cultured skin fibroblasts from 25 untreated patients with non‐Hodgkin's lymphoma (NHL) and 26 controls. The mean frequencies of aberrant cells, and gap, break, and gap+break events per 100 metaphases were 4.2, 1.9, 2.8, and 4.7 in the NHL group, and 5.1, 2.6, 3.2, and 5.8 in the control group. None of these parameters differed significantly between the groups, indicating that constitutional chromosomal instability is not related to the development of NHL. In the total material there was a significant (P<0.05) increase with age in the number of aberrant cells.
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- MERTENS, FREDRIKSkåne University Hospital(Swepub:lu)kgen-fme (author)
- HEIM, SVERRESkåne University Hospital(Swepub:lu)klin-she (author)
- KRISTOFFERSSON, ULFSkåne University Hospital(Swepub:lu)kgen-ukr (author)
- MANDAHL, NILSSkåne University Hospital(Swepub:lu)kgen-nma (author)
- OLSSON, HÅKANLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)onk-hol (author)
- MITELMAN, FELIXSkåne University Hospital(Swepub:lu)kgen-fmi (author)
- Avdelningen för klinisk genetikInstitutionen för laboratoriemedicin (creator_code:org_t)
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- In:Hereditas: Springer Science and Business Media LLC109:2, s. 277-2800018-0661
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