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Acetabular dysplasi...
Acetabular dysplasia and the risk of developing hip osteoarthritis at 2,5,8, and 10 years follow-up in a prospective nationwide cohort study (CHECK).
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- Riedstra, N. S. (author)
- Erasmus University Medical Center
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- Vinge, R. (author)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Höftsjukdomar från vaggan till protesen,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund OsteoArthritis Division - Hip diseases from the cradle to the prosthesis,Lund University Research Groups
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- Herfkens, J. (author)
- Erasmus University Medical Center
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- Eygendaal, D. (author)
- Erasmus University Medical Center
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- Bierma-Zeinstra, S. M.A. (author)
- Erasmus University Medical Center
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- Runhaar, J. (author)
- Erasmus University Medical Center
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- van Buuren, M. M.A. (author)
- Erasmus University Medical Center
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- Agricola, R. (author)
- Erasmus University Medical Center
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(creator_code:org_t)
- Elsevier BV, 2023
- 2023
- English.
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In: Seminars in Arthritis and Rheumatism. - : Elsevier BV. - 0049-0172. ; 60
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http://dx.doi.org/10... (free)
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https://doi.org/10.1...
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Abstract
Subject headings
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- Objective: To assess the relationship between acetabular dysplasia (AD) and the risk of incident and end-stage radiographic hip osteoarthritis (RHOA) over 2,5,8 and 10 years. Design: Individuals (n = 1002) aged between 45 and 65 from the prospective Cohort Hip and Cohort Knee (CHECK) were studied. Anteroposterior pelvic radiographs were obtained at baseline and 2,5,8, and 10-years follow-up. False profile radiographs were obtained at baseline. AD was defined as a lateral center edge angle, an anterior center edge angle, or both <25° at baseline. The risk of developing RHOA was determined at each follow-up moment. Incident RHOA was defined by Kellgren & Lawrence (KL) grade ≥2 or total hip replacement (THR), end-stage RHOA by a KL grade ≥3 or THR. Associations were expressed in odds ratios (OR) using logistic regression with generalized estimating equations. Results: AD was associated with the development of incident RHOA at 2 years follow-up (OR 2.46, 95% CI 1.00–6.04), 5 years follow-up (OR 2.28, 95% CI 1.20–4.31), and 8 years follow-up (OR 1.86, 95%CI 1.22–2.83). AD was only associated with end-stage RHOA at 5 years follow-up (OR 3.75, 95% CI 1.02–13.77). No statistically significant associations were observed between AD and RHOA at 10-years follow-up. Conclusion: Baseline AD in individuals between 45 and 65 years is associated with an increased risk of developing RHOA within 2- and 5 years. However, this association seems to weaken after 8 years and disappears after 10 years.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Keyword
- Developmental dysplasia
- Diagnostic imaging
- Epidemiology
- Hip shape
- Morphology
- Risk factor
Publication and Content Type
- art (subject category)
- ref (subject category)
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