Search: onr:"swepub:oai:lup.lub.lu.se:c99c04f2-fc6a-464b-868c-23c0c844993a" >
The dynamics of gen...
The dynamics of genomic-length DNA molecules in 100-nm channels
-
- Tegenfeldt, Jonas (author)
- Lund University,Lunds universitet,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
-
- Prinz, Christelle (author)
- Lund University,Lunds universitet,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
-
Cao, H (author)
-
show more...
-
Chou, S (author)
-
Reisner, WW (author)
-
Riehn, R (author)
-
Wang, YM (author)
-
Cox, EC (author)
-
Sturm, JC (author)
-
Silberzan, P (author)
-
Austin, RH (author)
-
show less...
-
(creator_code:org_t)
- 2004-07-13
- 2004
- English.
-
In: Proceedings of the National Academy of Sciences. - : Proceedings of the National Academy of Sciences. - 1091-6490 .- 0027-8424. ; 101:30, s. 10979-10983
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://europepmc.or...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- We show that genomic-length DNA molecules imaged in nano-channels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers. This fundamental relationship allows us to measure directly the contour length of single DNA molecules confined in the channels, and the statistical analysis of the dynamics of the polymer in the nanochannel allows us to compute the SD of the mean of the extension. This statistical analysis allows us to measure the extension of A DNA multimers with a 130-nm SD in 1 min.
Subject headings
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Tegenfeldt, Jona ...
-
Prinz, Christell ...
-
Cao, H
-
Chou, S
-
Reisner, WW
-
Riehn, R
-
show more...
-
Wang, YM
-
Cox, EC
-
Sturm, JC
-
Silberzan, P
-
Austin, RH
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Physical Science ...
-
and Condensed Matter ...
- Articles in the publication
-
Proceedings of t ...
- By the university
-
Lund University