Search: onr:"swepub:oai:lup.lub.lu.se:d26e2d83-f4ea-439c-bbf9-f0b87083c156" > Atopy patch test re...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04514naa a2200481 4500 | |
001 | oai:lup.lub.lu.se:d26e2d83-f4ea-439c-bbf9-f0b87083c156 | |
003 | SwePub | |
008 | 160401s2003 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:1959055 | |
024 | 7 | a https://lup.lub.lu.se/record/1125302 URI |
024 | 7 | a https://doi.org/10.1046/j.1365-2133.2003.05093.x2 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19590552 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Johansson, C.u Karolinska Institutet4 aut |
245 | 1 0 | a Atopy patch test reactions to Malassezia allergens differentiate subgroups of atopic dermatitis patients. |
264 | 1 | b Oxford University Press (OUP),c 2003 |
338 | a electronic2 rdacarrier | |
520 | a Background The yeast Malassezia is considered to be one of the factors that can contribute to atopic dermatitis (AD). Objectives To investigate the reactivity to Malassezia allergens, measured as specific serum IgE, positive skin prick test and positive atopy patch test (APT), in adult patients with AD. Methods In total, 132 adult patients with AD, 14 with seborrhoeic dermatitis (SD) and 33 healthy controls were investigated for their reactions to M. sympodialis extract and three recombinant Malassezia allergens (rMal s 1, rMal s 5 and rMal s 6). Results Sixty-seven per cent of the AD patients, but only one of the SD patients and none of the healthy controls, showed a positive reaction to at least one of the Malassezia allergens (extract and/or recombinant allergens) in at least one of the tests. The levels of M. sympodialis-specific IgE in serum correlated with the total serum IgE levels. Elevated serum levels of M. sympodialis-specific IgE were found in 55% and positive APT reactions in 41% of the AD patients with head and neck dermatitis. A relatively high proportion of patients without head and neck dermatitis and patients with low total serum IgE levels had a positive APT for M. sympodialis, despite lower proportions of individuals with M. sympodialis-specific IgE among these groups of patients. Conclusions These results support that Malassezia can play a role in eliciting and maintaining eczema in patients with AD. The addition of an APT to the test battery used in this study reveals a previously overlooked impact of Malassezia hypersensitivity in certain subgroups of AD patients. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng |
700 | 1 | a Sandström, M.H.4 aut |
700 | 1 | a Bartosik, Jaceku Lund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)derm-jba |
700 | 1 | a Särnhult, T.4 aut |
700 | 1 | a Christiansen, J4 aut |
700 | 1 | a Zargari, A.u Karolinska Institutet4 aut |
700 | 1 | a Bäck, Oveu Lund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)derm-oba |
700 | 1 | a Wahlgren, C.F.u Karolinska Institutet4 aut |
700 | 1 | a Faergemann, J.4 aut |
700 | 1 | a Scheynius, A.u Karolinska Institutet4 aut |
700 | 1 | a Tengvall Linder, M.u Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutetb Dermatologi och venereologi, Lund4 org |
773 | 0 | t British Journal of Dermatologyd : Oxford University Press (OUP)g 148:3, s. 479-488q 148:3<479-488x 1365-2133x 0007-0963 |
856 | 4 | u https://portal.research.lu.se/files/2738270/623710.pdfx primaryx freey FULLTEXT |
856 | 4 | u http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12653739&dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1046/j.1365-2133.2003.05093.xy FULLTEXT |
856 | 4 | u https://lup.lub.lu.se/search/files/2738270/623710.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/112530 |
856 | 4 8 | u https://doi.org/10.1046/j.1365-2133.2003.05093.x |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1959055 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Copy and save the link in order to return to this view