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Prognostic importan...
Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes
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Alexander, JH (author)
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Harrington, RA (author)
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Bhapkar, M (author)
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Mahaffey, KW (author)
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Lincoff, AM (author)
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Ohman, EM (author)
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Klootwijk, P (author)
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- Pahlm, Olle (author)
- Lund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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Henden, B (author)
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Deckers, JW (author)
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Simoons, ML (author)
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Califf, RM (author)
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Wagner, GS (author)
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(creator_code:org_t)
- Elsevier BV, 2003
- 2003
- English.
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In: American Journal of Medicine. - : Elsevier BV. - 0002-9343. ; 115:8, s. 613-619
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Abstract
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- PURPOSE: to investigate the prognostic importance of new small Q waves following an acute coronary syndrome. METHODS: We assessed 6-month mortality in 10,501 patients with non-ST-elevation acute coronary syndromes who had survived 30 days and had both admission and 30-day electrocardiograms. Patients were stratified by whether they had no new Q waves (n = 9447), new 30- to 40-ms Q waves (n = 733), or new greater than or equal to40-ms Q waves (n = 321). RESULTS: Mortality was higher in patients with 30- to 40-ms Q waves than in those with no new Q waves (3.4% [25/733] vs. 2.4% [227/9447], P = 0.005), and even higher in those with greater than or equal to40-ms Q waves (5.3% [17/321], P = 0.002). After adjustment for baseline risk predictors, mortality remained higher in patients with new 30- to 40-ms Q waves (odds ratio [OR] = 1.30; 95% confidence interval [CI]: 0.85 to 1.98; P = 0.23) and those with new greater than or equal to40-ms Q waves (OR = 1.87; 95% Cl: 1.13 to 3.09; P = 0.01). CONCLUSION: Patients with new small Q waves following a non-ST-elevation acute coronary syndrome are at increased risk of adverse outcomes. These small Q waves should be considered diagnostic of myocardial infarction. Further research should investigate whether even smaller QRS changes are prognostically important. (C)2003 by Excerpta Medica Inc.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Alexander, JH
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Harrington, RA
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Bhapkar, M
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Mahaffey, KW
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Lincoff, AM
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Ohman, EM
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show more...
-
Klootwijk, P
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Pahlm, Olle
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Henden, B
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Deckers, JW
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Simoons, ML
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Califf, RM
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Wagner, GS
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Respiratory Medi ...
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Lund University