Search: onr:"swepub:oai:lup.lub.lu.se:d436dc6e-dbdc-44a4-8364-efdedd1b4dce" >
The Relationships b...
-
O'Connor, Daryl B
(author)
The Relationships between Sex Hormones and Sexual Function in Middle-Aged and Older European Men.
- Article/chapterEnglish2011
Publisher, publication year, extent ...
-
The Endocrine Society,2011
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:d436dc6e-dbdc-44a4-8364-efdedd1b4dce
-
https://lup.lub.lu.se/record/2150921URI
-
https://doi.org/10.1210/jc.2010-2216DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
Context: Limited data are available exploring the associations between sex hormones, multiple domains of sexual functioning, and sexual function-related distress in nonpatient samples in Europe. Objectives: The aim of the study was to investigate the relationships between serum testosterone (T), estradiol (E2), and dihydrotestosterone (DHT) and sexual function in a multicenter population-based study of aging in men. Design: Using stratified random sampling, 2838 men aged 40-79 yr completed the European Male Ageing Study-Sexual Function Questionnaire and provided a blood sample for hormone measurements. T, E2, and DHT were measured using gas chromatography-mass spectrometry. Setting: We conducted a community-based population survey in eight European centers. Main Outcome Measures: Self-reported sexual function (overall sexual function, sexual function-related distress, erectile dysfunction, masturbation) was measured. Results: Total and free T, but not E2 or DHT, was associated with overall sexual function in middle-aged and older men. E2 was the only hormone associated with sexual function-related distress such that higher levels were related to greater distress. Free T levels were associated with masturbation frequency and erectile dysfunction in the fully adjusted models, such that higher T was associated with less dysfunction and greater frequency. Moreover, there was a T threshold for the relationship between total T, sexual function, and erectile dysfunction. At T concentrations of 8 nmol/liter or less, T was associated with worse sexual functioning, whereas at T levels over 8 nmol/liter, the relationship came to a plateau. Conclusions: These findings suggest that different hormonal mechanisms may regulate sexual functioning (T) vs. the psychological aspects (E2) of male sexual behavior. Moreover, there was a T threshold for overall sexual function such that at levels greater than 8 nmol/liter the relationship between T and sexual function did not become stronger.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Lee, David M
(author)
-
Corona, Giovanni
(author)
-
Forti, Gianni
(author)
-
Tajar, Abdelouahid
(author)
-
O'Neill, Terence W
(author)
-
Pendleton, Neil
(author)
-
Bartfai, Gyorgy
(author)
-
Boonen, Steven
(author)
-
Casanueva, Felipe F
(author)
-
Finn, Joseph D
(author)
-
Giwercman, AleksanderLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine(Swepub:lu)kir-agi
(author)
-
Han, Thang S
(author)
-
Huhtaniemi, Ilpo T
(author)
-
Kula, Krzysztof
(author)
-
Labrie, Fernand
(author)
-
Lean, Michael E J
(author)
-
Punab, Margus
(author)
-
Silman, Alan J
(author)
-
Vanderschueren, Dirk
(author)
-
Wu, Frederick C W
(author)
-
Institutionen för translationell medicinMedicinska fakulteten
(creator_code:org_t)
Related titles
-
In:The Journal of clinical endocrinology and metabolism: The Endocrine Society96, s. 1577-15871945-71970021-972X
Internet link
Find in a library
To the university's database
- By the author/editor
-
O'Connor, Daryl ...
-
Lee, David M
-
Corona, Giovanni
-
Forti, Gianni
-
Tajar, Abdelouah ...
-
O'Neill, Terence ...
-
show more...
-
Pendleton, Neil
-
Bartfai, Gyorgy
-
Boonen, Steven
-
Casanueva, Felip ...
-
Finn, Joseph D
-
Giwercman, Aleks ...
-
Han, Thang S
-
Huhtaniemi, Ilpo ...
-
Kula, Krzysztof
-
Labrie, Fernand
-
Lean, Michael E ...
-
Punab, Margus
-
Silman, Alan J
-
Vanderschueren, ...
-
Wu, Frederick C ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Endocrinology an ...
- Articles in the publication
-
The Journal of c ...
- By the university
-
Lund University