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Green banana protection of gastric mucosa against experimentally induced injuries in rats

Dunji, B. S. (author)
Lund University
Svensson, I. (author)
Lund University,Lunds universitet,Livsmedelsteknik,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bioteknik,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Department of Food Technology, Engineering and Nutrition,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Biotechnology,Center for Applied Life Sciences,Department of Chemistry,Faculty of Engineering, LTH
Axelson, J. (author)
Lund University,Lunds universitet,Livsmedelsteknik,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Kirurgi,Forskargrupper vid Lunds universitet,Bioteknik,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Department of Food Technology, Engineering and Nutrition,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Surgery,Lund University Research Groups,Biotechnology,Center for Applied Life Sciences,Department of Chemistry,Faculty of Engineering, LTH
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Adlercreutz, P. (author)
Lund University,Lunds universitet,Livsmedelsteknik,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bioteknik,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Department of Food Technology, Engineering and Nutrition,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Biotechnology,Center for Applied Life Sciences,Department of Chemistry,Faculty of Engineering, LTH
Ar'rajab, A. (author)
Lund University
Larsson, K. (author)
Lund University,Lunds universitet,Livsmedelsteknik,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bioteknik,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Department of Food Technology, Engineering and Nutrition,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Biotechnology,Center for Applied Life Sciences,Department of Chemistry,Faculty of Engineering, LTH
Bengmark, S. (author)
Lund University,Lunds universitet,Livsmedelsteknik,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bioteknik,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Department of Food Technology, Engineering and Nutrition,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Biotechnology,Center for Applied Life Sciences,Department of Chemistry,Faculty of Engineering, LTH
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 (creator_code:org_t)
2009-07-08
1993
English 5 s.
In: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 28:10, s. 894-898
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The protective capacities of fresh green (unripe) sweet bananas and of phosphatidylcholine and pectin (banana ingredients) against acute (ethanol- or indomethacin-induced) and chronic (indomethacin-induced) gastric mucosal lesions were evaluated in rats. Banana pulp was mixed with saline and given by gavage, as a pretreatment in a single dose. The identical protocol was used for pectin and phosphatidylcholine solution, and the dosages were adjusted to equal the amount of ingredients in the banana mixture, but higher concentrations were also given. The banana suspension reduced acute lesions, as did pectin and phosphatidylcholine in higher concentrations, but in concentrations as in fresh fruit no protective effects were observed except by pectin against indomethacin injury. In the model of chronic ulcers the banana suspension provided an incomplete and temporary protective effect. We conclude that the protective capacity of fresh green sweet bananas cannot be confined to only one active component. Pectin and phosphatidylcholine may protect gastric mucosa by strengthening the mucous-phospholipid layer, but the mechanism of protection afforded by bananas has to be further elucidated.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Keyword

Banana fruit
Chronic ulcer
Ethanol
Gastric mucosa
Indomethacin
Mucosal erosions
Mucosal protection
Pectin
Phosphatidylcholine

Publication and Content Type

art (subject category)
ref (subject category)

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