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  • Danielsen, Stine A (author)

Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis.

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2014-07-19
  • Oxford University Press (OUP),2015
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:d55f9678-30ec-4c72-8c5a-e0cd07230499
  • https://lup.lub.lu.se/record/4581914URI
  • https://doi.org/10.1093/neuonc/nou140DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Malignant peripheral nerve sheath tumor (MPNST) is a rare and highly aggressive disease with no evidence of effect from adjuvant therapy. It is further associated with the hereditary syndrome neurofibromatosis type 1 (NF1). Silencing of the tumor suppressor gene RASSF1A through DNA promoter hypermethylation is known to be involved in cancer development, but its impact in MPNSTs remains unsettled.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Lind, Guro E (author)
  • Kolberg, Matthias (author)
  • Høland, Maren (author)
  • Bjerkehagen, Bodil (author)
  • Sundby Hall, Kirsten (author)
  • van den Berg, Eva (author)
  • Mertens, FredrikLund University,Lunds universitet,Avdelningen för klinisk genetik,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Clinical Genetics,Department of Laboratory Medicine,Faculty of Medicine(Swepub:lu)kgen-fme (author)
  • Smeland, Sigbjørn (author)
  • Picci, Piero (author)
  • Lothe, Ragnhild A (author)
  • Avdelningen för klinisk genetikInstitutionen för laboratoriemedicin (creator_code:org_t)

Related titles

  • In:Neuro-Oncology: Oxford University Press (OUP)17:1, s. 63-691523-58661522-8517

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