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- Eriksson, MarieUmeå universitet,Medicin (author)
Functional outcome 3 months after stroke predicts long-term survival
- Article/chapterEnglish2008
Publisher, publication year, extent ...
- 2008-03-17
- S. Karger AG,2008
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:d587a1f1-280c-4a8f-9920-2f086a905e6c
- https://lup.lub.lu.se/record/1201445URI
- https://doi.org/10.1159/000121343DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-19411URI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-103571URI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Background: When reporting stroke survival and prognostic factors with a possible effect on outcome, the starting point for the observation of a clinical cohort usually is the onset of stroke or the acute admission of a patient. Thus, acute and early mortality inflict prognosis on long-term outcome. In order to give a more robust analysis of long-term survival after the acute period we chose to start our observation with 3-month survivors. Methods: We used data from Riks-Stroke, the Swedish quality register for stroke care, together with survival information from the Swedish population register to explore the influence of disability level 3 months after stroke on long-term survival. The main analysis included 15,959 stroke patients, registered during 2001-2002, who had been independent in primary activities of daily living before stroke, had suffered an ischaemic or a haemorrhagic stroke and reported no previous stroke. Results: Impaired functional outcome after stroke was an independent predictor of poor survival. Patients with modified Rankin scale (mRS) grades 3, 4 and 5 had hazard ratios of 1.7, 2.5 and 3.8, respectively, as compared with patients with lower mRS grades. In addition to high mRS, male sex, high age, diabetes, smoking, hypertension therapy at stroke onset, atrial fibrillation and depressed mood were also recognized as significant predictors of poor survival using a multiple Cox regression model. Conclusion: The influence of disability on survival is stronger than that of several other well-known prognostic factors. This finding indicates that any intervention in the acute phase that may improve functional status at 3 months will also have favourable secondary effects on survival in the long term.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
- stroke
- registries
- functional recovery
- stroke outcome
- outcome assessment
- MEDICINE
Added entries (persons, corporate bodies, meetings, titles ...)
- Norrving, BoLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)neur-bno (author)
- Terént, AndreasUppsala universitet,Institutionen för medicinska vetenskaper(Swepub:uu)andrtere (author)
- Stegmayr, BirgittaUmeå universitet,Medicin (author)
- Umeå universitetMedicin (creator_code:org_t)
Related titles
- In:Cerebrovascular Diseases: S. Karger AG25:5, s. 423-4291421-97861015-9770
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