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Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells.
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- Winslow, Sofia (author)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine
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- Leandersson, Karin (author)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Cancerimmunologi, Malmö,Forskargrupper vid Lunds universitet,Experimentell patologi, Malmö,Department of Translational Medicine,Faculty of Medicine,Cancer Immunology, Malmö,Lund University Research Groups,Experimental Pathology, Malmö
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- Larsson, Christer (author)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine
- (creator_code:org_t)
- 2013-12-09
- 2013
- English.
- In: Molecular Cancer. - : Springer Science and Business Media LLC. - 1476-4598. ; 12:1
- Journal article (peer-reviewed)
Abstract
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- Regulation of mRNAs is one way to control protein levels and thereby important cellular processes such as growth, invasion and apoptosis. G3BPs constitute a family of mRNA-binding proteins, shown to be overexpressed in several cancer types, including breast, colon and pancreas cancer. G3BP has been reported to both stabilize and induce degradation of specific mRNAs.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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