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Culturing and patch...
Culturing and patch clamping of Jurkat T cells and neurons on Al 2 O 3 coated nanowire arrays of altered morphology
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- Harberts, Jann (author)
- University of Hamburg
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- Zierold, Robert (author)
- University of Hamburg
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- Fendler, Cornelius (author)
- University of Hamburg
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- Koitmäe, Aune (author)
- University of Hamburg
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- Bayat, Parisa (author)
- University of Hamburg
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- Fernandez-Cuesta, Irene (author)
- University of Hamburg
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- Loers, Gabriele (author)
- University Medical Center Hamburg-Eppendorf
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- Diercks, Björn Philipp (author)
- University Medical Center Hamburg-Eppendorf
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- Fliegert, Ralf (author)
- University Medical Center Hamburg-Eppendorf
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- Guse, Andreas H. (author)
- University Medical Center Hamburg-Eppendorf
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- Ronning, Carsten (author)
- Friedrich Schiller University Jena
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- Otnes, Gaute (author)
- Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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- Borgström, Magnus (author)
- Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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- Blick, Robert H. (author)
- University of Wisconsin-Madison,University of Hamburg
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(creator_code:org_t)
- 2019
- 2019
- English 8 s.
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In: RSC Advances. - : Royal Society of Chemistry (RSC). - 2046-2069. ; 9:20, s. 11194-11201
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Abstract
Subject headings
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- Nanowire substrates play an increasingly important role for cell cultures as an approach for hybrid bio-semiconductor junctions. We investigate Jurkat T cells and neurons from mice cultured on Al 2 O 3 coated ordered and randomly distributed nanowires. Cell viability was examined by life/membrane staining reporting comparable viability on planar and nanowire substrates. Imaging the hybrid interface reveals a wrapping of the cell membrane around the very nanowire tip. Patch clamp recordings show similar electrophysiological responses on each type of nanowires compared to planar control substrates. We demonstrate that the morphological characteristic of the nanowire substrate plays a subordinate role which opens up the arena for a large range of nanowire substrates in a functionalized application such as stimulation or sensing.
Subject headings
- NATURVETENSKAP -- Biologi -- Cellbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Cell Biology (hsv//eng)
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Harberts, Jann
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Zierold, Robert
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Fendler, Corneli ...
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Koitmäe, Aune
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Bayat, Parisa
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Fernandez-Cuesta ...
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show more...
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Loers, Gabriele
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Diercks, Björn P ...
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Fliegert, Ralf
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Guse, Andreas H.
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Ronning, Carsten
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Otnes, Gaute
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Borgström, Magnu ...
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Blick, Robert H.
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Cell Biology
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Physical Science ...
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and Condensed Matter ...
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RSC Advances
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Lund University