Vacuum-Assisted wound closure and mesh-mediated fascial traction for open abdomen therapy - a systematic review

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Acosta, StefanLund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups (author)

Vacuum-Assisted wound closure and mesh-mediated fascial traction for open abdomen therapy - a systematic review

Article/chapterEnglish2017

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2017
7 s.

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LIBRIS-ID:oai:lup.lub.lu.se:e253c86c-8fad-471e-b216-902f7bd24b35
https://lup.lub.lu.se/record/e253c86c-8fad-471e-b216-902f7bd24b35URI
https://doi.org/10.5603/AIT.a2017.0023DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-334973URI

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Language:English
Summary in:English

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Background: The aim of this paper was to review the literature on vacuum-Assisted wound closure and mesh-mediated fascial traction (VAWCM) in open abdomen therapy. It was designed as systematic review of observational studies. Methods: A Pub Med, EMBASE and Cochrane search from 2007/01-2016/07 was performed combining the Medical Subject Headings "vacuum", "mesh-mediated fascial traction", "temporary abdominal closure", "delayed abdominal closure", "open abdomen", "abdominal compartment syndrome", "negative pressure wound therapy" or "vacuum assisted wound closure". Results: Eleven original studies were found including patients numbering from 7 to 111. Six studies were prospective and five were retrospective. Nine studies were on mixed surgical (n = 9), vascular (n = 6) and trauma (n = 6) patients, while two were exclusively on vascular patients. The primary fascial closure rate per protocol varied from 80-100%. The time to closure of the open abdomen varied between 9-32 days. The entero-Atmospheric fistula rate varied from 0-10.0%. The in-hospital survival rate varied from 57-100%. In the largest prospective study, the incisional hernia rate among survivors at 63 months of median follow-up was 54% (27/50), and 16 (33%) repairs out of 48 incisional hernias were performed throughout the study period. The study patients reported lower short form health survey (SF-36) scores than the mean reference population, mainly dependent on the prevalence of major co-morbidities. There was no difference in SF-36 scores or a modified ventral hernia pain questionnaire (VHPQ) at 5 years of follow up between those with versus those without incisional hernias. Conclusions: A high primary fascial closure rate can be achieved with the vacuum-Assisted wound closure and meshmediated fascial traction technique in elderly, mainly non-Trauma patients, in need of prolonged open abdomen therapy.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kirurgi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Surgery hsv//eng
Mesh-Mediated Fascial Traction
Negative Pressure Wound Therapy
Open Abdomen
Temporary Abdominal Closure
Vacuum
mesh-mediated fascial traction

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Björck, MartinUppsala universitet,Uppsala University,Kärlkirurgi(Swepub:uu)mabjo425 (author)
Petersson, UlfLund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups(Swepub:lu)med-ufp (author)
Vaskulära sjukdomar - kliniska studierForskargrupper vid Lunds universitet (creator_code:org_t)

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In:Anaesthesiology Intensive Therapy49:2, s. 139-1451642-57581731-2515

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By the author/editor: Acosta, Stefan; Björck, Martin; Petersson, Ulf

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Surgery

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By the university: Lund University; Uppsala University

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