Search: onr:"swepub:oai:lup.lub.lu.se:e7ded4f5-d919-4d79-9c67-e3263f98f4cf" >
Impaired immune fun...
Impaired immune function accompanies social evolution in spiders
-
- Bechsgaard, Jesper (author)
- Aarhus University
-
- Jorgensen, Tove Hedegaard (author)
- Aarhus University
-
- Jønsson, Anne Katrine (author)
- Aarhus University
-
show more...
-
- Schou, Mads (author)
- Lund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Molekylär ekologi och evolution,Forskargrupper vid Lunds universitet,Department of Biology,Faculty of Science,Molecular Ecology and Evolution Lab,Lund University Research Groups
-
- Bilde, Trine (author)
- Aarhus University
-
show less...
-
(creator_code:org_t)
- 2022-12-21
- 2022
- English 1 s.
-
In: Biology letters. - : The Royal Society. - 1744-9561 .- 1744-957X. ; 18:12, s. 20220331-20220331
- Related links:
-
http://dx.doi.org/10... (free)
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- An efficient immune system is essential to the survival of many animals. Sociality increases risk of pathogen transmission, which should select for enhanced immune function. However, two hypotheses instead predict a weakened immune function: relaxed selection caused by social immunity/protection, and reduced efficacy of selection due to inbreeding, reproductive skew and female bias in social species that reduce effective population size and accelerate genetic drift. We assessed the effect of social evolution on immune function in a comparative study of two social spider species and their closely related subsocial sister species (genus Stegodyphus). The haemolymph of social species was less efficient in inhibiting bacterial growth of the potentially pathogenic bacteria Bacillus subtilis than that of subsocial species. Reduced efficacy of selection in social species was supported by comparative genomic analysis showing substantially elevated non-synonymous substitutions in immune genes in one of the social species. We propose that impaired immune function results from reduced efficacy of selection because the evolution of sociality in spiders is accompanied by demographic processes that elevate genetic drift. Positive feedback between pathogen-induced local extinctions and the resulting elevation of genetic drift may further weaken responses to selection by pathogens, and threaten species persistence.
Subject headings
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Keyword
- comparative genomics
- haemolymph assay
- immunity
- social spider
- sociality
- subsocial spider
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database