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Diels-Alder adducts derived from the natural phthalide Z-ligustilide

Lager, Erik (author)
Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
Sundin, Anders (author)
Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
Toscano, Ruben A. (author)
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Delgado, Guillermo (author)
Sterner, Olov (author)
Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
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 (creator_code:org_t)
Elsevier BV, 2007
2007
English.
In: Tetrahedron Letters. - : Elsevier BV. - 0040-4039. ; 48:24, s. 4215-4218
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Z-Ligustilide, a naturally occurring phthalide isolated from Ligusticum porteri, underwent Diels-Alder reactions with different dienophiles yielding novel tricyclic products with potentially interesting biological properties. Where selectivity was possible, the reactions performed showed regio- and stereoselectivity. The experimental results with ethyl acrylate were compared with the selectivity predicted by ab initio calculations.

Subject headings

NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Keyword

STAT3
Z-ligustilide
galiellalactone
ab initio
Diels-Alder

Publication and Content Type

art (subject category)
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