Primary screening for human papillomavirus compared with cytology screening for cervical cancer in European settings: cost effectiveness analysis based on a Dutch microsimulation model

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:lup.lub.lu.se:eb925b0a-f610-4af7-bbee-d7fbcd832678" > Primary screening f...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

de Kok, Inge M. C. M. (author)

Primary screening for human papillomavirus compared with cytology screening for cervical cancer in European settings: cost effectiveness analysis based on a Dutch microsimulation model

Article/chapterEnglish2012

Publisher, publication year, extent ...

2012-03-05
BMJ,2012
electronicrdacarrier

Numbers

LIBRIS-ID:oai:lup.lub.lu.se:eb925b0a-f610-4af7-bbee-d7fbcd832678
https://lup.lub.lu.se/record/2517119URI
https://doi.org/10.1136/bmj.e670DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:124188106URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:art swepub-publicationtype
Subject category:ref swepub-contenttype

Notes

Objectives To investigate, using a Dutch model, whether and under what variables framed for other European countries screening for human papillomavirus (HPV) is preferred over cytology screening for cervical cancer, and to calculate the preferred number of examinations over a woman's lifetime. Design Cost effectiveness analysis based on a Dutch simulation model. Base case analyses investigated the cost effectiveness of more than 1500 different screening policies using the microsimulation model. Subsequently, the policies were compared for five different scenarios that represent different possible scenarios (risk of cervical cancer, previous screening, quality associated test characteristics, costs of testing, and prevalence of HPV). Setting Various European countries. Population Unvaccinated women born between 1939 and 1992. Main outcome measures Optimal screening strategy in terms of incremental cost effectiveness ratios (costs per quality adjusted life years gained) compared with different cost effectiveness thresholds, for two levels of sensitivity and costs of the HPV test. Results Primary HPV screening was the preferred primary test over the age of 30 in many considered scenarios. Primary cytology screening was preferred only in scenarios with low costs of cytology and in scenarios with a high prevalence of HPV in combination with high costs of HPV testing. Conclusions Most European countries should consider switching from primary cytology to HPV screening for cervical cancer. HPV screening must, however, only be implemented in situations where screening is well controlled.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

van Rosmalen, Joost (author)
Dillner, JoakimKarolinska Institutet,Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups(Swepub:lu)mikr-jdi (author)
Arbyn, Marc (author)
Sasieni, Peter (author)
Iftner, Thomas (author)
van Ballegooijen, Marjolein (author)
Klinisk mikrobiologi, MalmöForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

In:BMJ: British Medical Journal: BMJ3441756-18330959-81381468-5833
In:BMJ: BMJ3440959-81381468-5833

Internet link

Find in a library

BMJ: British Medical Journal (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: de Kok, Inge M. ...; van Rosmalen, Jo ...; Dillner, Joakim; Arbyn, Marc; Sasieni, Peter; Iftner, Thomas; show more...; van Ballegooijen ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Microbiology in ...

Articles in the publication: BMJ: British Med ...; BMJ

By the university: Lund University; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se