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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04154naa a2200397 4500 | |
| 001 | oai:lup.lub.lu.se:ec597a19-0dab-43a9-a9f8-ed45e14a32a3 | |
| 003 | SwePub | |
| 008 | 190827s2019 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/ec597a19-0dab-43a9-a9f8-ed45e14a32a32 URI |
| 024 | 7 | a https://doi.org/10.1016/j.nicl.2019.1019692 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Heggdal, Peder O.Laugenu University of Bergen,Haukeland University Hospital4 aut |
| 245 | 1 0 | a An fMRI-study on single-sided deafness : Spectral-temporal properties and side of stimulation modulates hemispheric dominance |
| 264 | 1 | b Elsevier BV,c 2019 |
| 520 | a Objective: Our main aim was to investigate the blood oxygenation level dependent (BOLD) response to monaural and binaural speech- and non-speech stimuli as measured with fMRI in subjects with single-sided deafness and in normal hearing controls. We hypothesised that the response to monaural stimulation in both normal hearing subjects and persons with single-sided deafness would vary with the complexity and nature of the stimuli and the side of stimulation. Design: Patients with left- and right single-sided deafness and controls with normal hearing receiving either binaural or monaural stimuli were tested using speech and non-speech auditory stimuli in an event-related fMRI experiment. Study sample: Twenty-two patients with single-sided deafness after treatment for vestibular schwannoma and 50 normal hearing controls. Results: Normal hearing persons receiving right side monaural stimuli activate bilateral temporal regions. Activation following left side monaural stimulation is more right lateralized. Persons with single-sided deafness respond similarly to controls to monaural stimulation. Persons with right side single-sided deafness show activation of frontal cortical regions not seen in persons with left side single-sided deafness following speech stimuli. This is possibly related to increased effort and more frequently reported problems with communication. Right side single-sided deafness is related to increased activation of areas usually related to processing of degraded input, including the thalamus. Conclusion: Hemispheric dominance following monaural auditory stimulation is modulated by the spectral-temporal properties of the stimuli and by which ear is stimulated. Differences between patients with right- and left side deafness suggests that right side deafness is related to increased activation of areas involved in processing of degraded input. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng |
| 653 | a fMRI | |
| 653 | a Hearing loss | |
| 653 | a Plasticity | |
| 653 | a Single-sided deafness | |
| 653 | a Vestibular schwannoma | |
| 700 | 1 | a Aarstad, Hans Jørgenu University of Bergen,Haukeland University Hospital4 aut |
| 700 | 1 | a Brännström, J.u Lund University,Lunds universitet,Logopedi, foniatri och audiologi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Kommunikation och kognition,Forskargrupper vid Lunds universitet,Logopedics, Phoniatrics and Audiology,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Communication and Cognition,Lund University Research Groups4 aut0 (Swepub:lu)ling-jbr |
| 700 | 1 | a Vassbotn, Flemming S.u Haukeland University Hospital4 aut |
| 700 | 1 | a Specht, Karstenu University of Bergen,UiT The Arctic University of Norway, Tromsø4 aut |
| 710 | 2 | a University of Bergenb Haukeland University Hospital4 org |
| 773 | 0 | t NeuroImage: Clinicald : Elsevier BVg 24q 24x 2213-1582 |
| 856 | 4 | u http://dx.doi.org/10.1016/j.nicl.2019.101969x freey FULLTEXT |
| 856 | 4 | u https://doi.org/10.1016/j.nicl.2019.101969 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/ec597a19-0dab-43a9-a9f8-ed45e14a32a3 |
| 856 | 4 8 | u https://doi.org/10.1016/j.nicl.2019.101969 |
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