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  • Johanneson, BUppsala universitet,Institutionen för genetik och patologi (author)

A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups

  • Article/chapterEnglish1999

Publisher, publication year, extent ...

  • Elsevier BV,1999

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:ecdb18cb-40b9-49fa-aa94-fd54fe4777f6
  • https://lup.lub.lu.se/record/1114837URI
  • https://doi.org/10.1006/jaut.1999.0305DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:1949966URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-51538URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Systemic lupus erythematosus is a disease of unknown etiology. Multiple genetic factors are believed to be involved in its pathogenesis. In addition, and due to genetic heterogeneity, these factors and/or their combinations may be different in different ethnic groups, while some might be shared between populations. We have performed genome scans in multicase families from three different population groups, two from Northern Europe, with a high degree of homogeneity, and the third from a recently admixed population of Mexican Mestizos. Although our family material is relatively small, the results presented here show that using family sets from well defined populations are sufficient to detect susceptibility loci for SLE. Our results also reveal the chromosomal regions most likely to contain susceptibility genes for SLE.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Steinsson, K (author)
  • Lindqvist, A KUppsala universitet,Karolinska Institutet,Institutionen för genetik och patologi (author)
  • Kristjansdottir, H (author)
  • Grondal, G (author)
  • Sandino, S (author)
  • Tjernström, FredrikLund University,Lunds universitet,Öron-, näs- och halssjukdomar, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Otorhinolaryngology (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)onh-ftj (author)
  • Sturfelt, GunnarLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)reum-gst (author)
  • Granados-Arriola, J (author)
  • Alcocer-Varela, J (author)
  • Lundberg, IKarolinska Institutet (author)
  • Jonasson, IUppsala universitet,Institutionen för genetik och patologi (author)
  • Truedsson, LennartLund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine(Swepub:lu)mmb-ltr (author)
  • Svenungsson, E (author)
  • Klareskog, L (author)
  • Alarcon-Segovia, D (author)
  • Johanneson, N (author)
  • Gyllensten, UBUppsala universitet,Institutionen för genetik och patologi (author)
  • Alarcon-Riquelme, MEUppsala universitet,Institutionen för genetik och patologi (author)
  • Uppsala universitetInstitutionen för genetik och patologi (creator_code:org_t)

Related titles

  • In:Journal of Autoimmunity: Elsevier BV13, s. 137-0896-8411
  • In:J Autoimmun: Elsevier BV13, s. 137-

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