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Fast multiecho bala...
Fast multiecho balanced SSFP metabolite mapping of H-1 and hyperpolarized C-13 compounds
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Leupold, Jochen (author)
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- Månsson, Sven (author)
- Lund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups
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Petersson, J. Stefan (author)
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Hennig, Juergen (author)
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Wieben, Oliver (author)
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(creator_code:org_t)
- 2009-04-15
- 2009
- English.
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In: Magma. - : Springer Science and Business Media LLC. - 1352-8661. ; 22:4, s. 251-256
- Related links:
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http://dx.doi.org/10...
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Abstract
Subject headings
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- To investigate the feasibility of multiecho balanced steady-state free precession (bSSFP)-based fast chemical shift mapping hyperpolarized C-13 metabolites. The overall goal was to reduce total imaging time and to increase spatial resolution compared to common chemical shift imaging (CSI). A multiecho bSSFP sequence in combination with an iterative reconstruction algorithm was implemented. H-1 experiments were performed on phantoms and on a human volunteer in order to investigate the feasibility of the method on a system with metabolite maps that are known beforehand. C-13 experiments were performed in vivo on pigs, where CSI images were acquired also for comparison. Chemical shift images of three and four distinct H-1 resonance frequencies as well as chemical shift images of up to five hyperpolarized C-13 metabolites were successfully obtained. Fast metabolite mapping based on multiecho balanced SSFP in combination with an iterative reconstruction approach could successfully separate several H-1 resonances and hyperpolarized C-13 metabolites.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- Hyperpolarized C-13
- IDEAL
- Multiecho sequence
- Balanced SSFP
- Chemical shift imaging
Publication and Content Type
- art (subject category)
- ref (subject category)
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