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Improved Segmentati...
Improved Segmentation of Deep Sulci in Cortical Gray Matter Using a Deep Learning Framework Incorporating Laplace’s Equation
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- Ravikumar, Sadhana (author)
- University of Pennsylvania
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- Ittyerah, Ranjit (author)
- University of Pennsylvania
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- Lim, Sydney (author)
- University of Pennsylvania
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- Xie, Long (author)
- University of Pennsylvania
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- Das, Sandhitsu (author)
- University of Pennsylvania
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- Khandelwal, Pulkit (author)
- University of Pennsylvania
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- Wisse, Laura E.M. (author)
- Lund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,LU Profile Area: Proactive Ageing,Lund University Profile areas
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- Bedard, Madigan L. (author)
- University of Pennsylvania
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- Robinson, John L. (author)
- University of Pennsylvania
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- Schuck, Terry (author)
- University of Pennsylvania
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- Grossman, Murray (author)
- University of Pennsylvania
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- Trojanowski, John Q. (author)
- University of Pennsylvania
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- Lee, Edward B. (author)
- University of Pennsylvania
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- Tisdall, M. Dylan (author)
- University of Pennsylvania
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- Prabhakaran, Karthik (author)
- University of Pennsylvania
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- Detre, John A. (author)
- University of Pennsylvania
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- Irwin, David J. (author)
- University of Pennsylvania
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- Trotman, Winifred (author)
- University of Pennsylvania
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- Mizsei, Gabor (author)
- University of Pennsylvania
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- Artacho-Pérula, Emilio (author)
- University of Castilla La Mancha
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- de Onzono Martin, Maria Mercedes Iñiguez (author)
- University of Castilla La Mancha
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- del Mar Arroyo Jiménez, Maria (author)
- University of Castilla La Mancha
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- Muñoz, Monica (author)
- University of Castilla La Mancha
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- Romero, Francisco Javier Molina (author)
- University of Castilla La Mancha
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- del Pilar Marcos Rabal, Maria (author)
- University of Castilla La Mancha
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- Cebada-Sánchez, Sandra (author)
- University of Castilla La Mancha
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- González, José Carlos Delgado (author)
- University of Castilla La Mancha
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- de la Rosa-Prieto, Carlos (author)
- University of Castilla La Mancha
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- Parada, Marta Córcoles (author)
- University of Castilla La Mancha
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- Wolk, David A. (author)
- University of Pennsylvania
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- Insausti, Ricardo (author)
- University of Castilla La Mancha
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- Yushkevich, Paul A. (author)
- University of Pennsylvania
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Frangi, Alejandro (editor)
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de Bruijne, Marleen (editor)
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Wassermann, Demian (editor)
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Navab, Nassir (editor)
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(creator_code:org_t)
- 2023
- 2023
- English 13 s.
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In: Information Processing in Medical Imaging - 28th International Conference, IPMI 2023, Proceedings. - 1611-3349 .- 0302-9743. - 9783031340475 ; 13939 LNCS, s. 692-704
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Abstract
Subject headings
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- When developing tools for automated cortical segmentation, the ability to produce topologically correct segmentations is important in order to compute geometrically valid morphometry measures. In practice, accurate cortical segmentation is challenged by image artifacts and the highly convoluted anatomy of the cortex itself. To address this, we propose a novel deep learning-based cortical segmentation method in which prior knowledge about the geometry of the cortex is incorporated into the network during the training process. We design a loss function which uses the theory of Laplace’s equation applied to the cortex to locally penalize unresolved boundaries between tightly folded sulci. Using an ex vivo MRI dataset of human medial temporal lobe specimens, we demonstrate that our approach outperforms baseline segmentation networks, both quantitatively and qualitatively.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Keyword
- Cortical segmentation
- ex vivo MRI
- topology correction
Publication and Content Type
- kon (subject category)
- ref (subject category)
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- By the author/editor
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Ravikumar, Sadha ...
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Ittyerah, Ranjit
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Lim, Sydney
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Xie, Long
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Das, Sandhitsu
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Khandelwal, Pulk ...
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show more...
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Wisse, Laura E.M ...
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Bedard, Madigan ...
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Robinson, John L ...
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Schuck, Terry
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Grossman, Murray
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Trojanowski, Joh ...
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Lee, Edward B.
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Tisdall, M. Dyla ...
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Prabhakaran, Kar ...
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Detre, John A.
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Irwin, David J.
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Trotman, Winifre ...
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Mizsei, Gabor
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Artacho-Pérula, ...
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de Onzono Martin ...
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del Mar Arroyo J ...
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Muñoz, Monica
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Romero, Francisc ...
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del Pilar Marcos ...
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Cebada-Sánchez, ...
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González, José C ...
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de la Rosa-Priet ...
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Parada, Marta Có ...
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Wolk, David A.
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Insausti, Ricard ...
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Yushkevich, Paul ...
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Frangi, Alejandr ...
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de Bruijne, Marl ...
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Wassermann, Demi ...
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Navab, Nassir
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Medical Image Pr ...
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Information Proc ...
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Lund University