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The feasibility of ...
The feasibility of salivary sample collection in an international pediatric cohort : The the TEDDY study
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- Roth, Roswith (author)
- Klinikum rechts der Isar,Helmholtz Zentrum München
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- Baxter, Judith (author)
- University of Colorado
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- Vehik, Kendra (author)
- University of South Florida
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- Hopkins, Diane (author)
- Medical College of Georgia
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- Killian, Michael (author)
- Pacific Northwest Research Institute
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- Gesualdo, Patricia (author)
- University of Colorado
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- Melin, Marie Jessica (author)
- Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups
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- Simell, Barbara (author)
- Turku University Hospital
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- Strauss, Elisabeth (author)
- Klinikum rechts der Isar,Helmholtz Zentrum München
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- Lernmark, Åke (author)
- Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups
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- Johnson, Suzanne Bennett (author)
- Florida State University
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(creator_code:org_t)
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- 2017-05-26
- 2017
- English 10 s.
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In: Developmental Psychobiology. - : Wiley. - 0012-1630. ; 59:5, s. 658-667
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Abstract
Subject headings
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- Saliva offers a relatively noninvasive method for measuring analytes such as cortisol, holding particular promise for use in pediatric populations on a large scale if a rigorous collection protocol is feasible in diverse settings. The Environmental Determinants of Diabetes in the Young study protocol, conducted in centers in the United States, Sweden, Finland, and Germany, used salivary collection to assess cortisol level as a physiologic marker of stress. Saliva was collected using Sorbettes from subjects at 3.5, 4.5, and 5.5 years of age. Parents collected a morning sample, and staff collected pre- and post-blood draw samples. Feasibility was assessed based on protocol completion, adherence with instructions, factors affecting adherence, and sufficiency of saliva sample for cortisol determination. Collection of saliva samples in a diverse pediatric population is feasible. Establishing non-invasive and acceptable methods for collecting physiological parameters of stress will allow better exploration of determinants of health in this important population.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- adherence
- methodological feasibility
- multi-center international
- pediatric cohort study
- salivary collection
- salivary cortisol
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Roth, Roswith
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Baxter, Judith
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Vehik, Kendra
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Hopkins, Diane
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Killian, Michael
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Gesualdo, Patric ...
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show more...
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Melin, Marie Jes ...
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Simell, Barbara
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Strauss, Elisabe ...
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Lernmark, Åke
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Johnson, Suzanne ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Developmental Ps ...
- By the university
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Lund University