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Transcatheter aorti...
Transcatheter aortic valve implantation in patients with small aortic annuli using a 20 mm balloon-expanding valve
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- Puri, Rishi (author)
- Laval University
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- Byrne, Jonathan (author)
- King's College Hospital
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- Muller, Ralf (author)
- HELIOS Klinikum Siegburg
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- Baumbach, Hardy (author)
- Robert-Bosch-Hospital
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- Eltchaninoff, Helene (author)
- Hopital Charles Nicolle
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- Redwood, Simon (author)
- Guy's and St Thomas' NHS Foundation Trust
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- Cheema, Asim (author)
- Saint Michael's Hospital
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- Dubois, Christophe (author)
- Catholic University of Leuven
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- Ihlberg, Leo (author)
- Helsinki University Central Hospital
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- Wijeysundera, Harindra C. (author)
- Sunnybrook Health Sciences Centre
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- Cerillo, Alfredo (author)
- Pasquinucci Hospital
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- Götberg, Matthias (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Klaaborg, Kaj Erik (author)
- Aarhus University Hospital
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- Pelletier, Marc (author)
- Horizon Health Network
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- Blanco-Mata, Roberto (author)
- Hospital de Cruces
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- Edwards, Richard (author)
- Freeman Hospital
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- Gandolfo, Caterina (author)
- A.R.N.A.S. Ospedali Civico
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- Muir, Douglas (author)
- James Cook University Hospital
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- Meucci, Francesco (author)
- Careggi University Hospital
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- Sinning, Jan Malte (author)
- University Hospital Bonn
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- Stella, Pieter (author)
- University Medical Center Utrecht
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- Veulemans, Verena (author)
- University Hospital of Düsseldorf
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- Virtanen, Marko (author)
- Tampere University Hospital
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- Regueiro, Ander (author)
- Laval University
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- Thoenes, Martin (author)
- Léman Research Institute
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- Pibarot, Philippe (author)
- Laval University
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- Pelletier-Beaumont, Emilie (author)
- Laval University
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- Rodés-Cabau, Josep (author)
- Laval University
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(creator_code:org_t)
- 2016-08-17
- 2017
- English 6 s.
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In: Heart. - : BMJ. - 1355-6037 .- 1468-201X. ; 103, s. 148-153
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http://dx.doi.org/10...
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Abstract
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- Background While transcatheter aortic valve implantation (TAVI) is established for treating highoperative risk surgical aortic valve replacement candidates, until recently the smallest transcatheter heart valve (THV) measured 23 mm, posing greater risk for annular rupture and THV failure in patients with aortic stenosis (AS) with small aortic annuli (=20 mm). Objectives In the setting of a multicentre registry, we report on the safety, efficacy and early clinical outcomes of the SAPIEN XT 20 mm balloon-expanding THV. Results Among TAVI 55 recipients (n=30 for native AS, n=25 for a valve-in-valve procedure (V-in-V)), median age and Society of Thoracic Surgeons score were 85 (81 to 87) years and 7.8 (4.7 to 12.4)%, respectively. Mean and minimum annular diameters were 19±1 and 17±2 mm, respectively, in native patients with AS, and 17±1 mm (internal diameter) in V-in-V recipients. Successful device implantation rate was 96%, with no procedural-related death. Overall in-hospital-30-day death, stroke and major bleeding rates were 5%, 2% and 9%, respectively. In native AS TAVI recipients, mean transaortic gradient decreased from 54±20 to 12±5 mm Hg ( p<0.001), and from 45±17 to 24±8 mm Hg (p<0.001) in V-in-V recipients. Severe prosthesis-patient mismatch (PPM) rates were 10% and 48% in native AS and V-in-V TAVI recipients, respectively ( p=0.03). Post-TAVI, the rate of moderate aortic regurgitation was 7% and 0% in native AS and V-in-V TAVI recipients, respectively. Conclusions TAVI with the 20 mm SAPIEN XT THV appears safe and technically feasible, with acceptable short-term clinical outcomes and low rates of severe PPM in those with native AS.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- aortic valve implantation
- Transcatheter
Publication and Content Type
- art (subject category)
- ref (subject category)
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Heart
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- By the author/editor
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Puri, Rishi
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Byrne, Jonathan
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Muller, Ralf
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Baumbach, Hardy
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Eltchaninoff, He ...
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Redwood, Simon
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show more...
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Cheema, Asim
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Dubois, Christop ...
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Ihlberg, Leo
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Wijeysundera, Ha ...
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Cerillo, Alfredo
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Götberg, Matthia ...
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Klaaborg, Kaj Er ...
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Pelletier, Marc
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Blanco-Mata, Rob ...
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Edwards, Richard
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Gandolfo, Cateri ...
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Muir, Douglas
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Meucci, Francesc ...
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Sinning, Jan Mal ...
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Stella, Pieter
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Veulemans, Veren ...
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Virtanen, Marko
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Regueiro, Ander
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Thoenes, Martin
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Pibarot, Philipp ...
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Pelletier-Beaumo ...
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Rodés-Cabau, Jos ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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Heart
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Lund University