The new cell irradiation facility at the Lund nuclear probe

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Arteaga, NataliaLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH (author)

The new cell irradiation facility at the Lund nuclear probe

Article/chapterEnglish2007

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Elsevier BV,2007

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LIBRIS-ID:oai:lup.lub.lu.se:f72bfcd6-e5aa-41e7-9a7d-35ddc5cd5a06
https://lup.lub.lu.se/record/647975URI
https://doi.org/10.1016/j.nimb.2007.01.255DOI

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Language:English
Summary in:English

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The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels with approximately 96% efficiency. This paper also reports target accuracy test results and the first non-targeted irradiation procedure performed at the Lund sub-micron beam line. (c) 2007 Elsevier B.V. All rights reserved.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Infektionsmedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Infectious Medicine hsv//eng
irradiation
single ions
cell
CELLION

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Pallon, JanLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-jpa (author)
Gram, MagnusLund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)medk-mo0 (author)
Auzelyte, VaidaLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-vau (author)
Elfman, MikaelLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-mel (author)
Kristiansson, PerLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-pkr (author)
Malmqvist, KlasLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-km0 (author)
Nilsson, ChristerLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-cni (author)
Wegdén, MarieLund University,Lunds universitet,Kärnfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Nuclear physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)nucl-mwe (author)
KärnfysikFysiska institutionen (creator_code:org_t)

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In:Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms: Elsevier BV260:1, s. 91-960168-583X

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By the author/editor: Arteaga, Natalia; Pallon, Jan; Gram, Magnus; Auzelyte, Vaida; Elfman, Mikael; Kristiansson, Pe ...; show more...; Malmqvist, Klas; Nilsson, Christe ...; Wegdén, Marie; show less...

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