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  • Dominguez, MevLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine (author)

Evaluation of MLH1 I219V Polymorphism in Unrelated South American Individuals Suspected of Having Lynch Syndrome.

  • Article/chapterEnglish2012

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  • 2012

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  • LIBRIS-ID:oai:lup.lub.lu.se:f862dbe9-2e3b-4efe-a5b6-250dfc90f21b
  • https://lup.lub.lu.se/record/3160802URI

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  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

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  • Some single-nucleotide polymorphisms are associated with higher risk of colorectal cancer development and are suggested to explain part of the genetic contribution to Lynch syndrome. Aim: To evaluate the mutL homolog 1 (MLH1) I219V polymorphism in 124 unrelated South American individuals suspected of having Lynch syndrome, based on frequency, association with pathogenic MLH1 and mutS homolog 2 (MSH2) mutation and clinical features.

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  • DA Silva, Felipe Carneiro (author)
  • Santos, Erika Maria Monteiro (author)
  • DA Silva, Sabrina Daniela (author)
  • DE Oliveira Ferreira, Fabio (author)
  • Junior, Samuel Aguiar (author)
  • Gomy, Israel (author)
  • Vaccaro, Carlos (author)
  • Redal, Maria Ana (author)
  • Della Valle, Adriana (author)
  • Sarroca, Carlos (author)
  • Rasmussen, Lene (author)
  • Carraro, Dirce Maria (author)
  • Rossi, Benedito Mauro (author)
  • Bröstcancer-genetikSektion I (creator_code:org_t)

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  • In:Anticancer research32:10, s. 4347-43511791-7530

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