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Persistent high pre...
Persistent high prevalence of thyroid antibodies after immunosuppressive therapy in subjects with glomerulonephritis. A prospective three-year follow-up study
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- Westman, K W (author)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Autoimmunitet och njursjukdomar,Forskargrupper vid Lunds universitet,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Autoimmunity and kidney diseases,Lund University Research Groups
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- Bygren, P G (author)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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Ericsson, U B (author)
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- Høier-Madsen, M (author)
- Danish Serum Institute, Copenhagen
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- Wieslander, J (author)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Erfurth, E M (author)
- Wieslab AB
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(creator_code:org_t)
- 1998-06-05
- 1998
- English.
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In: American Journal of Nephrology. - : S. Karger AG. - 0250-8095 .- 1421-9670. ; 18:4, s. 9-274
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Abstract
Subject headings
Close
- The prevalence of thyroid antibodies, indicating an autoimmune thyroiditis, has been shown to be significantly increased in patients with autoimmune diseases. A 3-year prospective follow-up study of 42 patients with biopsy-confirmed glomerulonephritis is presented. Although the majority of patients had been treated with immunosuppressants, the prevalence of thyroid peroxidase antibodies was unchanged in both females and males, 47 and 15% respectively, at follow-up. Likewise, the prevalence of thyroglobulin antibodies was unaffected as was that of antinuclear antibodies (ANA) when analysing males and females together. However, for males there was a trend to higher prevalence for ANA at follow-up. On the other hand, the prevalence of antineutrophil cytoplasmic antibodies declined. Furthermore, thyroid antibodies were not restricted to membranous nephropathy, and notably found in 4 out of the 8 patients with vasculitis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Adult
- Antibodies, Antineutrophil Cytoplasmic/analysis
- Autoantibodies/analysis
- Female
- Follow-Up Studies
- Glomerulonephritis/drug therapy
- Humans
- Immunosuppressive Agents/therapeutic use
- Iodide Peroxidase/immunology
- Male
- Middle Aged
- Prevalence
- Prospective Studies
- Thyroglobulin/immunology
- Thyroid Gland/immunology
- Thyroiditis, Autoimmune/epidemiology
- Time Factors
Publication and Content Type
- art (subject category)
- ref (subject category)
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