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Use of snus and acu...
Use of snus and acute myocardial infarction: pooled analysis of eight prospective observational studies
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Hansson, Jenny (author)
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- Galanti, Maria Rosaria (author)
- Karolinska Institutet
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Hergens, Maria-Pia (author)
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Fredlund, Peeter (author)
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- Ahlbom, Anders (author)
- Karolinska Institutet
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- Alfredsson, Lars (author)
- Karolinska Institutet
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- Bellocco, Rino (author)
- Karolinska Institutet
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- Eriksson, Marie (author)
- Karolinska Institutet,Umeå universitet,Statistik
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- Hallqvist, Johan (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Hedblad, Bo (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
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- Jansson, Jan-Håkan (author)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Nilsson, Peter (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Pedersen, Nancy (author)
- Karolinska Institutet
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- Lagerros, Ylva Trolle (author)
- Karolinska Institutet
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- Ostergren, Per-Olof (author)
- Lund University,Lunds universitet,Socialmedicin och global hälsa,Forskargrupper vid Lunds universitet,Social Medicine and Global Health,Lund University Research Groups
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- Magnusson, Cecilia (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2012-06-22
- 2012
- English.
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In: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 1573-7284 .- 0393-2990. ; 27:10, s. 771-779
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Abstract
Subject headings
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- The use of snus (also referred to as Scandinavian or Swedish moist smokeless tobacco), which is common in Sweden and increasing elsewhere, is receiving increasing attention since considered a tobacco smoke "potential reduction exposure product". Snus delivers a high dose of nicotine with possible hemodynamic effects, but its impact on cardiovascular morbidity and mortality is uncertain. The aim of this study was to investigate whether snus use is associated with risk of and survival after acute myocardial infarction (AMI). Data from eight prospective cohort studies set in Sweden was pooled and reanalysed. The relative risk of first time AMI and 28-day case-fatality was calculated for 130,361 men who never smoked. During 2,262,333 person-years of follow-up, 3,390 incident events of AMI were identified. Current snus use was not associated with risk of AMI (pooled multivariable hazard ratio 1.04, 95 % confidence interval 0.93 to 1.17). The short-term case fatality rate appeared increased in snus users (odds ratio 1.28, 95 % confidence interval 0.99 to 1.68). This study does not support any association between use of snus and development of AMI. Hence, toxic components other than nicotine appear implicated in the pathophysiology of smoking related ischemic heart disease. Case fatality after AMI is seemingly increased among snus users, but this relationship may be due to confounding by socioeconomic or life style factors.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Acute myocardial infarction
- Smokeless tobacco
- Snus
- The Swedish
- collaboration on health effects of snus use
- Acute myocardial infarction
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Hansson, Jenny
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Galanti, Maria R ...
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Hergens, Maria-P ...
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Fredlund, Peeter
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Ahlbom, Anders
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Alfredsson, Lars
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Bellocco, Rino
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Eriksson, Marie
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Hallqvist, Johan
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Hedblad, Bo
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Jansson, Jan-Håk ...
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Nilsson, Peter
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Pedersen, Nancy
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Lagerros, Ylva T ...
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Ostergren, Per-O ...
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Magnusson, Cecil ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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European Journal ...
- By the university
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Lund University
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Umeå University
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Karolinska Institutet
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Uppsala University