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- Hansson, ChristerLund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine (author)
Stereochemical Considerations on Concomitant Allergic Contact Dermatitis to Ester of the CIS-TRANS Isomeric Compounds Maleic Acid and Fumaric Acid.
- Article/chapterEnglish2003
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- 2003-03-21
- S. Karger AG,2003
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- LIBRIS-ID:oai:lup.lub.lu.se:ff88f3f2-10ab-4e19-aa6a-435347f420a1
- https://lup.lub.lu.se/record/112800URI
- https://doi.org/10.1159/000069027DOI
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- Language:English
- Summary in:English
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- Allergic contact dermatitis from esters of fumaric acid or esters of maleic acid is rare. The case of a chemist with allergic reactions to esters both of fumaric acid and of maleic acid is presented. Extremely high sensitivity of the patient to diethyl fumarate was noted. The formation of identical complete antigens from esters of these two <i>cis-trans</i> isomeric acids may be an explanation of the patient’s double allergy. This is discussed from a stereochemical point of view. These stereochemical considerations point to a general mechanism where <i>cis-trans</i> isomeric α,β-unsaturated carbonyl compounds are converted into the same complete antigen.
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- Thörneby-Andersson, K (author)
- Dermatologi och venereologi, LundSektion III (creator_code:org_t)
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- In:Skin Pharmacology and Applied Skin Physiology: S. Karger AG16:2, s. 117-1221422-2868
- In:Skin Pharmacology and Physiology: S. Karger AG16:2, s. 117-1221660-55271660-5535
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