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- Pennanen, C (author)
The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: a voxel-based morphometric study
- Article/chapterEnglish2006
Publisher, publication year, extent ...
- 2006-06-19
- S. Karger AG,2006
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- LIBRIS-ID:oai:prod.swepub.kib.ki.se:112469987
- http://kipublications.ki.se/Default.aspx?queryparsed=id:112469987URI
- https://doi.org/10.1159/000093263DOI
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- Language:English
- Summary in:English
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- We investigated the effect of apolipoprotein E (ApoE) on the whole brain in 51 individuals with mild cognitive impairment using voxel-based morphometry. Between cases heterozygous for the ApoE Ε4 (n = 15) and those who were ApoE Ε4 noncarriers (n = 28), only the right parahippocampal gyrus, with the entorhinal cortex included, reached the level of statistical significance. In cases homozygous for the Ε4 allele (n = 8) versus noncarriers, the greatest atrophy was located in the right amygdala followed by the right parahippocampal gyrus, the left amygdala and the left medial dorsal thalamic nucleus.
Added entries (persons, corporate bodies, meetings, titles ...)
- Testa, C (author)
- Boccardi, M (author)
- Laakso, MP (author)
- Hallikainen, M (author)
- Helkala, EL (author)
- Hanninen, T (author)
- Kivipelto, MKarolinska Institutet (author)
- Kononen, M (author)
- Nissinen, A (author)
- Tervo, S (author)
- Vanhanen, M (author)
- Vanninen, R (author)
- Frisoni, GB (author)
- Soininen, H (author)
- Karolinska Institutet (creator_code:org_t)
Related titles
- In:Dementia and geriatric cognitive disorders: S. Karger AG22:1, s. 60-661420-80081421-9824
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- Hanninen, T
- Kivipelto, M
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