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Anxiety disorders and rheumatic Fever: is there an association?
- Seixas, AAA (author)
- Hounie, AG (author)
- Fossaluza, V (author)
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- Curi, M (author)
- Alvarenga, PG (author)
- De Mathis, MA (author)
- De Mathis, ME (author)
- Pauls, D (author)
- Pereira, CAD (author)
- Miguel, EC (author)
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- (creator_code:org_t)
- 2014-11-07
- 2008
- English.
- In: CNS spectrums. - : Cambridge University Press (CUP). - 1092-8529 .- 2165-6509. ; 13:12, s. 1039-
- Journal article (peer-reviewed)
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- Introduction:Findings suggest that obsessive-compulsive disorder (OCD) and related disorders, referred to as obsessive-compulsive spectrum disorders (OCSDs), are more common in patients with rheumatic fever (RF).Objectives:To determine whether RF or Sydenham's chorea increases the probability of anxiety disorders in the relatives of individuals with RF with and without SC.Methods:This was a case-control family study in which 98 probands and 389 first-degree relatives (FDRs) were assessed using structured psychiatric interviews. A Poisson regression model was used to determine whether the presence of any disorder in one family member influences the rate of disorders in the remaining family members.Results:Generalized anxiety disorder (GAD) occurred more frequently in the FDRs of RF probands than in those of control probands (P=.018). The presence of RF, GAD, or separation anxiety disorder in one family member significantly increased the chance of OCSDs in another member of the family.
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- Seixas, AAA
- Hounie, AG
- Fossaluza, V
- Curi, M
- Alvarenga, PG
- De Mathis, MA
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- De Mathis, ME
- Vallada, H
- Pauls, D
- Pereira, CAD
- Miguel, EC
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