Search: onr:"swepub:oai:prod.swepub.kib.ki.se:120167341" >
Emerging role of ne...
Emerging role of neuregulin as a modulator of muscle metabolism
-
Guma, A (author)
-
- Martinez-Redondo, V (author)
- Karolinska Institutet
-
Lopez-Soldado, I (author)
-
show more...
-
Canto, C (author)
-
Zorzano, A (author)
-
show less...
-
(creator_code:org_t)
- American Physiological Society, 2010
- 2010
- English.
-
In: American journal of physiology. Endocrinology and metabolism. - : American Physiological Society. - 1522-1555 .- 0193-1849. ; 298:4, s. E742-E750
- Related links:
-
http://kipublication...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Neuregulin was described initially as a neurotrophic factor involved in the formation of the neuromuscular junction in skeletal muscle. However, in recent years, neuregulin has been reported to be a myokine that exerts relevant effects on myogenesis and the regulation of muscle metabolism. In this new context, the rapid and chronic metabolic effects of neuregulin appear to be related to muscle contraction. Indeed, the effects of neuregulin resemble those of exercise, which are accompanied by an improvement in insulin sensitivity. In this review, we challenge the classical role assigned to neuregulin in muscle and propound the emerging concept of its involvement in the regulation of energetic metabolism and insulin responsiveness.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database