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Elevated pro-brain ...
Elevated pro-brain natriuretic peptide, troponin T and malnutrition inflammatory score in chronic hemodialysis patients with overt cardiovascular disease
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Trimarchi, H (author)
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Muryan, A (author)
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Campolo-Girard, V (author)
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Dicugno, M (author)
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Barucca, N (author)
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Lombi, F (author)
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Young, P (author)
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Pomeranz, V (author)
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Forrester, M (author)
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Alonso, M (author)
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Iriarte, R (author)
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Diaz, ML (author)
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- Lindholm, B (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2010-08-30
- 2011
- English.
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In: Nephron. Clinical practice. - : S. Karger AG. - 1660-2110. ; 117:3, s. C198-C205
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https://doi.org/10.1...
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Abstract
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- <i>Background:</i> We assessed the relationship between pro-brain natriuretic peptide (pro-BNP), troponin T (TropT) and nutritional status. <i>Methods:</i> A total of 48 chronic hemodialysis patients were grouped according to the presence [group A (GA); n = 24] or not [group B (GB)] of cardiovascular disease. <i>Results:</i> Compared to GB subjects, GA subjects were older, had been on hemodialysis for a longer period and had higher prevalences of vascular grafts, hypertension and elevated C-reactive protein (CRP) [GA vs. GB: 1.1 (range 0.1–32.9) vs. 0.4 (0–28.1) mg/dl; p = 0.028], malnutrition inflammatory score (MIS) (GA vs. GB: 7.50 vs. 4.00; p = 0.001), pro-BNP [GA vs. GB: 6,760 (601–103,200) vs. 686 (75–83,700) pg/ml; p < 0.001] and TropT [GA vs. GB: 0.3650 (0.011–0.199) vs. 0.010 (0.0–0.290) ng/ml; p = 0.002]. Pro-BNP correlated with TropT (rho 0.539; p < 0.001), MIS (rho 0.502; p < 0.0001), homocysteine (rho 0.321; p = 0.13) and CRP (rho 0.511; p < 0.0001). Pro-BNP levels were lower in GB patients as the body mass index increased; the opposite occurred in GA. <i>Conclusions:</i> Patients with cardiovascular disease had elevated pro-BNP and TropT levels. In patients without cardiovascular disease, malnutrition and inflammation were associated with vascular prostheses, while pro-BNP was lower in obese patients.
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- By the author/editor
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Trimarchi, H
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Muryan, A
-
Campolo-Girard, ...
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Dicugno, M
-
Barucca, N
-
Lombi, F
-
show more...
-
Young, P
-
Pomeranz, V
-
Forrester, M
-
Alonso, M
-
Iriarte, R
-
Diaz, ML
-
Lindholm, B
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show less...
- Articles in the publication
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Nephron. Clinica ...
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Karolinska Institutet