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Host-gut microbiota...
Host-gut microbiota metabolic interactions
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Nicholson, JK (author)
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Holmes, E (author)
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Kinross, J (author)
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Burcelin, R (author)
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Gibson, G (author)
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Jia, W (author)
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- Pettersson, S (author)
- Karolinska Institutet
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2012
- 2012
- English.
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In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 336:6086, s. 1262-1267
- Related links:
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http://kipublication...
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https://doi.org/10.1...
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Abstract
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- The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the gut, liver, muscle, and brain. A deeper understanding of these axes is a prerequisite for optimizing therapeutic strategies to manipulate the gut microbiota to combat disease and improve health.
Publication and Content Type
- ref (subject category)
- art (subject category)
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