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Long-term mortality in a cohort of home-dwelling elderly with mild Alzheimer's disease and Lewy body dementia

Oesterhus, R (author)
Soennesyn, H (author)
Rongve, A (author)
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Ballard, C (author)
Aarsland, D (author)
Karolinska Institutet
Vossius, C (author)
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 (creator_code:org_t)
2014-04-08
2014
English.
In: Dementia and geriatric cognitive disorders. - : S. Karger AG. - 1421-9824 .- 1420-8008. ; 38:3-4, s. 161-169
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • <b><i>Objective:</i></b> To study mortality in subjects with mild dementia in Norway with a special focus on patients with Lewy body dementia (LBD) compared to Alzheimer's disease (AD). <b><i>Methods:</i></b> All referrals of mild dementia patients to dementia clinics in western Norway from March 2005 to March 2007 were included and followed until December 2012. Diagnoses were based on a comprehensive standardized assessment program. <b><i>Results:</i></b> Of 209 patients, 137 (66%) had AD and 53 (25%) had LBD. Dementia was associated with increased mortality (standardized mortality ratio = 1.8, AD 1.5, LBD 2.6). The median survival time was 6.2 years (95% CI 5.4-6.9). Predictors of mortality were age at diagnosis (HR 1.1 per year) and LBD diagnosis (HR 2.4). <b><i>Conclusion:</i></b> Dementia patients had an increased mortality, particularly those with LBD.

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