Comparison of Macular Thickness in Patients with Keratoconus and Control Subjects Using the Cirrus HD-OCT

Cervino, A (author)

Miller, WL (author)

Bergmanson, J (author)

(creator_code:org_t)

Hindawi Limited, 2015
2015
English.
In: BioMed research international. - : Hindawi Limited. - 2314-6141 .- 2314-6133. ; 2015, s. 832863-

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Abstract Subject headings

Purpose.The aim of the present study was to compare macular thickness in patients with keratoconus (KC) with macular thickness in healthy subjects.Subjects and Methods.Twenty-six patients with KC and 52 control subjects were included. The macular structure was evaluated using a Zeiss Cirrus HD-OCT. The scan pattern used was 512 × 128, which covers an area of approximately 6 × 6 mm of the retina. The cube volume was assessed as well as macular thickness in each of the 9 sectors defined by the software.Results.The mean signal strength was significantly lower in the KC group (mean 8.4, range 6–10) compared with the control group (mean 9.7, range 7–10),P<0.0001(unpairedt-test). There were no significant differences in cube volume (unpairedt-test), cube average thickness, or macular thickness between the KC group and the control subjects in any of the retinal locations (one-way ANOVA).Conclusion.Macular structure as measured by OCT in KC subjects should be expected to lie within the range of age and sex matched controls.

By the author/editor: Brautaset, RL; Rosen, R; Cervino, A; Miller, WL; Bergmanson, J; Nilsson, M

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