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Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates

Garcia, YR (author)
Iyer, A (author)
Van Lysebetten, D (author)
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Pabon, YV (author)
Karolinska Institutet
Louage, B (author)
Honcharenko, M (author)
Karolinska Institutet
De Geest, BG (author)
Smith, CIE (author)
Karolinska Institutet
Stromberg, R (author)
Karolinska Institutet
Madder, A (author)
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 (creator_code:org_t)
2015
2015
English.
In: Chemical communications (Cambridge, England). - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; 51:99, s. 17552-17555
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • DNA recognition is achieved by graphting two GCN4 basic region peptides onto a cholic acid scaffold ensuring a correct binding geometry combined with enhanced cell uptake.

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