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Nickel and blood co...
Nickel and blood counts in workers exposed to urban stressors
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Rosati, MV (author)
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Casale, T (author)
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Ciarrocca, M (author)
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- Weiderpass, E (author)
- Karolinska Institutet
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Capozzella, A (author)
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Schifano, MP (author)
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Tomei, F (author)
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Nieto, HA (author)
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Marrocco, M (author)
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Tomei, G (author)
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Caciari, T (author)
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Sancini, A (author)
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(creator_code:org_t)
- 2014-07-07
- 2016
- English.
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In: Toxicology and industrial health. - : SAGE Publications. - 1477-0393 .- 0748-2337. ; 32:6, s. 987-997
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https://doi.org/10.1...
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Abstract
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- Nickel (Ni) and Ni compounds are widely present in the urban air. The purpose of this study is to estimate exposure of individuals to Ni and the correlation between this exposure and the values of blood counts in outdoor workers. This study focused on a sample of 101 outdoor workers (55 male and 46 female; 65 nonsmokers and 36 smokers), all employed in the municipal police in a large Italian city. The personal levels of exposure to Ni were assessed through (a) environmental monitoring of Ni present in the urban air obtained from individual samples and (b) biological monitoring of urinary and blood Ni. The blood count parameters were obtained from the hemochromocytometric tests. Pearson correlation coefficients ( r) were calculated to assess the association between the blood and urinary Ni and the complete blood count. Multiple linear regression models were used to examine the associations between the complete blood count and the independent variables (age, gender, years of work for current tasks, cigarette smoking habit (current and never smoker), values of airborne Ni, and blood and urinary Ni). Multiple linear regression analysis performed on the total group of 101 subjects confirms the association among the red blood cells count, the hematocrit, and the urinary Ni ( R2 = 0.520, p = 0.025 and R2 = 0.530, p = 0.030). These results should lead to further studies on the effects of Ni in working populations exposed to urban pollutants. The possibility that the associations found in our study may be partially explained by other urban pollutants (such as benzene, toluene, and other heavy metals) not taken into consideration in this study cannot be ruled out.
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Rosati, MV
-
Casale, T
-
Ciarrocca, M
-
Weiderpass, E
-
Capozzella, A
-
Schifano, MP
-
show more...
-
Tomei, F
-
Nieto, HA
-
Marrocco, M
-
Tomei, G
-
Caciari, T
-
Sancini, A
-
show less...
- Articles in the publication
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Toxicology and i ...
- By the university
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Karolinska Institutet