Search: onr:"swepub:oai:prod.swepub.kib.ki.se:136279851" > Rationale and desig...
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000 | 03619naa a2200793 4500 | |
001 | oai:prod.swepub.kib.ki.se:136279851 | |
003 | SwePub | |
008 | 240701s2017 | |||||||||||000 ||eng| | |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1362798512 URI |
024 | 7 | a https://doi.org/10.2217/pgs-2017-00352 DOI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Farzan, N4 aut |
245 | 1 0 | a Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium |
264 | 1 | b Future Medicine Ltd,c 2017 |
520 | a Aim: International collaboration is needed to enable large-scale pharmacogenomics studies in childhood asthma. Here, we describe the design of the Pharmacogenomics in Childhood Asthma (PiCA) consortium. Materials & methods: Investigators of each study participating in PiCA provided data on the study characteristics by answering an online questionnaire. Results: A total of 21 studies, including 14,227 children/young persons (58% male), from 12 different countries are currently enrolled in the PiCA consortium. Fifty six percent of the patients are Caucasians. In total, 7619 were inhaled corticosteroid users. Among patients from 13 studies with available data on asthma exacerbations, a third reported exacerbations despite inhaled corticosteroid use. In the future pharmacogenomics studies within the consortium, the pharmacogenomics analyses will be performed separately in each center and the results will be meta-analyzed. Conclusion: PiCA is a valuable platform to perform pharmacogenetics studies within a multiethnic pediatric asthma population. | |
700 | 1 | a Vijverberg, SJ4 aut |
700 | 1 | a Andiappan, AK4 aut |
700 | 1 | a Arianto, L4 aut |
700 | 1 | a Berce, V4 aut |
700 | 1 | a Blanca-Lopez, N4 aut |
700 | 1 | a Bisgaard, H4 aut |
700 | 1 | a Bonnelykke, K4 aut |
700 | 1 | a Burchard, EG4 aut |
700 | 1 | a Campo, P4 aut |
700 | 1 | a Canino, G4 aut |
700 | 1 | a Carleton, B4 aut |
700 | 1 | a Celedon, JC4 aut |
700 | 1 | a Chew, FT4 aut |
700 | 1 | a Chiang, WC4 aut |
700 | 1 | a Cloutier, MM4 aut |
700 | 1 | a Daley, D4 aut |
700 | 1 | a Den Dekker, HT4 aut |
700 | 1 | a Dijk, NF4 aut |
700 | 1 | a Duijts, L4 aut |
700 | 1 | a Flores, C4 aut |
700 | 1 | a Forno, E4 aut |
700 | 1 | a Hawcutt, DB4 aut |
700 | 1 | a Hernandez-Pacheco, N4 aut |
700 | 1 | a de Jongste, JC4 aut |
700 | 1 | a Kabesch, M4 aut |
700 | 1 | a Koppelman, GH4 aut |
700 | 1 | a Manolopoulos, VG4 aut |
700 | 1 | a Melen, Eu Karolinska Institutet4 aut |
700 | 1 | a Mukhopadhyay, S4 aut |
700 | 1 | a Nilsson, Su Karolinska Institutet4 aut |
700 | 1 | a Palmer, CN4 aut |
700 | 1 | a Pino-Yanes, M4 aut |
700 | 1 | a Pirmohamed, M4 aut |
700 | 1 | a Potocnki, U4 aut |
700 | 1 | a Raaijmakers, JA4 aut |
700 | 1 | a Repnik, K4 aut |
700 | 1 | a Schieck, M4 aut |
700 | 1 | a Sio, YY4 aut |
700 | 1 | a Smyth, RL4 aut |
700 | 1 | a Szalai, C4 aut |
700 | 1 | a Tantisira, KG4 aut |
700 | 1 | a Turner, S4 aut |
700 | 1 | a van der Schee, MP4 aut |
700 | 1 | a Verhamme, KM4 aut |
700 | 1 | a Maitland-van der Zee, AH4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Pharmacogenomicsd : Future Medicine Ltdg 18:10, s. 931-943q 18:10<931-943x 1744-8042x 1462-2416 |
856 | 4 | u https://europepmc.org/articles/pmc5967359?pdf=render |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:136279851 |
856 | 4 8 | u https://doi.org/10.2217/pgs-2017-0035 |
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