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Incidence and preva...
Incidence and prevalence of psoriatic arthritis in Denmark: a nationwide register linkage study
- Article/chapterEnglish2017
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:136405177
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136405177URI
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https://doi.org/10.1136/annrheumdis-2016-210963DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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To examine the incidence and temporal trends of psoriatic arthritis (PsA) in the general population in Denmark.MethodsUsing nationwide registry data, we estimated the number of patients with incident PsA within each 1-year period between 1997 and 2011 and calculated the rate of PsA cases within gender and age subgroups. Incidence rates were presented per 100 000 person-years.ResultsThere was a female predominance ranging from 50.3% (1998) to 59.2% (2010), and the mean age at time of diagnosis was 47–50 years. We identified a total of 12 719 patients with PsA (prevalence=0.22%), including 9034 patients where the PsA diagnosis was made by a rheumatologist (prevalence=0.16%). Incidence rates of PsA (per 100 000 person-years) increased from 7.3 in 1997 to a peak incidence of 27.3 in 2010. Incidence rates were highest for women and patients aged 50–59 years, respectively. The use of systemic non-biologic agents, that is, methotrexate, leflunomide, ciclosporin or sulfasalazine increased over the 15-year study course and were used in 66.3% of all patients. Biologic agents (etanercept, infliximab, adalimumab, certolizumab pegol, golimumab or ustekinumab) were used in 17.7% of patients with PsA.ConclusionsWe found a clear trend of rising PsA incidence on a national level. While the cause remains unclear, our findings might be explained by increased attention by patients and physicians.
Added entries (persons, corporate bodies, meetings, titles ...)
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Kristensen, LE
(author)
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Thyssen, JP
(author)
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Gislason, GH
(author)
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Gottlieb, AB
(author)
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Coates, LC
(author)
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Jullien, D
(author)
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Gisondi, P
(author)
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Gladman, DD
(author)
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Skov, L
(author)
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Mallbris, LKarolinska Institutet
(author)
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Karolinska Institutet
(creator_code:org_t)
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In:Annals of the rheumatic diseases: BMJ76:9, s. 1591-15971468-20600003-4967
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Egeberg, A
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Kristensen, LE
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Thyssen, JP
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Gislason, GH
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Gottlieb, AB
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Coates, LC
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show more...
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Jullien, D
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Gisondi, P
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Gladman, DD
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Skov, L
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Mallbris, L
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Annals of the rh ...
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Karolinska Institutet