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  • de Bruin, LMO (author)

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • American Society of Hematology,2018

Numbers

  • LIBRIS-ID:oai:prod.swepub.kib.ki.se:138764967
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:138764967URI
  • https://doi.org/10.1182/blood-2017-12-820985DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Mice with hypomorphic mutations in the Rag1 C-terminal domain are a model of leaky combined immunodeficiency with autoantibodies. Hypomorphic C-terminal domain Rag1 mutations cause repertoire skewing at the earliest stages of B- and T-cell development.

Added entries (persons, corporate bodies, meetings, titles ...)

  • Bosticardo, M (author)
  • Barbieri, A (author)
  • Lin, SG (author)
  • Rowe, JH (author)
  • Poliani, PL (author)
  • Ching, K (author)
  • Eriksson, DKarolinska Institutet (author)
  • Landegren, NKarolinska Institutet (author)
  • Kampe, OKarolinska Institutet (author)
  • Manis, JP (author)
  • Notarangelo, LD (author)
  • Karolinska Institutet (creator_code:org_t)

Related titles

  • In:Blood: American Society of Hematology132:3, s. 281-2921528-00200006-4971

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  • Blood (Search for host publication in LIBRIS)

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By the author/editor
de Bruin, LMO
Bosticardo, M
Barbieri, A
Lin, SG
Rowe, JH
Poliani, PL
show more...
Ching, K
Eriksson, D
Landegren, N
Kampe, O
Manis, JP
Notarangelo, LD
show less...
Articles in the publication
Blood
By the university
Karolinska Institutet

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