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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 32401naa a2205737 4500 | |
| 001 | oai:prod.swepub.kib.ki.se:142198309 | |
| 003 | SwePub | |
| 008 | 240701s2019 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-397418 | |
| 009 | oai:lup.lub.lu.se:673d0f2c-31e3-4a1d-8590-c463e479d317 | |
| 009 | oai:hhs.se:1158892420006056 | |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1421983092 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-019-12283-62 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3974182 URI |
| 024 | 7 | a https://lup.lub.lu.se/record/673d0f2c-31e3-4a1d-8590-c463e479d3172 URI |
| 024 | 7 | a https://research.hhs.se/esploro/outputs/journalArticle/Associations-of-autozygosity-with-a-broad/9910015063995060562 URI |
| 040 | a (SwePub)kid (SwePub)uud (SwePub)lud (SwePub)hhs | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Clark, DWu Univ Edinburgh, Usher Inst, Ctr Global Hlth Res, Edinburgh, Midlothian, Scotland,University of Edinburgh4 aut |
| 245 | 1 0 | a Associations of autozygosity with a broad range of human phenotypes |
| 264 | c 2019-10-31 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2019 |
| 500 | a For complete list of authors see http://dx.doi.org/10.1038/s41467-019-12283-6 | |
| 506 | a http://creativecommons.org/licenses/by/4.0/ | |
| 520 | a In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Annan klinisk medicin0 (SwePub)302992 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Other Clinical Medicine0 (SwePub)302992 hsv//eng |
| 700 | 1 | a Okada, Yu Osaka University4 aut |
| 700 | 1 | a Moore, KHSu Hadassah Medical Center,Children's Hospital of Philadelphia,Oulu University Hospital,Technical University of Munich,UCLA Medical Center,Medical University of Graz,Dr. Hari Singh Gour University,RMIT University,Amgen4 aut |
| 700 | 1 | a Mason, Du Harvard University,Johns Hopkins Medicine,University Medical Center Utrecht,University of Oxford,Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, BD96RJ, UK4 aut |
| 700 | 1 | a Pirastu, Nu University of Edinburgh4 aut |
| 700 | 1 | a Gandin, Iu University of Trieste4 aut |
| 700 | 1 | a Mattsson, Hu University of Helsinki4 aut |
| 700 | 1 | a Barnes, CLKu University of Edinburgh,University of Oxford,University of Cambridge,Peking University,Agency for Science, Technology and Research4 aut |
| 700 | 1 | a Lin, Ku University of Michigan–Ann Arbor,University of North Carolina at Chapel Hill4 aut |
| 700 | 1 | a Zhao, JHu University of Cambridge,Oulu University Hospital,Shanghai Jiao Tong University4 aut |
| 700 | 1 | a Deelen, Pu University of Groningen4 aut |
| 700 | 1 | a Rohde, Ru University of North Carolina at Chapel Hill,University of Michigan–Ann Arbor,Queensland University of Technology,University of Cambridge,University of Otago,Genomic,Imperial College London,University of Maryland, Baltimore,University Medical Center Utrecht,National Institutes of Health,Queen Mary University of London,Johns Hopkins Medicine,University of Oklahoma Health Sciences Center4 aut |
| 700 | 1 | a Schurmann, Cu Mount Sinai Hospital,National Institutes of Health,Diabetes Unit, K.E.M. Hospital Research Centre, Pune, MAH, 411011, India,University of Edinburgh4 aut |
| 700 | 1 | a Guo, XQu UCLA Medical Center4 aut |
| 700 | 1 | a Giulianini, Fu Brigham and Women's Hospital4 aut |
| 700 | 1 | a Zhang, WHu National University of Singapore,Imperial College London4 aut |
| 700 | 1 | a Medina-Gomez, Cu Istituto Neurologico Mediterraneo,Erasmus MC4 aut |
| 700 | 1 | a Karlsson, Ru Karolinska Institutet4 aut |
| 700 | 1 | a Bao, Yu UCLA Medical Center,University of Essex4 aut |
| 700 | 1 | a Bartz, TMu University of Helsinki,Technical University of Munich,Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy,University of Bern,Humboldt-Universität zu Berlin,University of Washington4 aut |
| 700 | 1 | a Baumbach, Cu Helmholtz Zentrum München4 aut |
| 700 | 1 | a Gyllensten, Ulf B.u Uppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik4 aut0 (Swepub:uu)ulfgyll |
| 700 | 1 | a Johannesson, Magnusu Stockholm School of Economics,Handelshögskolan i Stockholm4 aut0 (Swepub:hhs)198@hhs.se |
| 700 | 1 | a Brumat, Mu Queen Mary University of London,University of Potsdam,University of Trieste4 aut |
| 700 | 1 | a Chai, JFu National University of Singapore4 aut |
| 700 | 1 | a Corre, Tu Vrije Universiteit Amsterdam,SIB Swiss Institute of Bioinformatics4 aut |
| 700 | 1 | a Cousminer, DLu Children's Hospital of Philadelphia4 aut |
| 700 | 1 | a Dekker, AMu National Institutes of Health,University of Aberdeen,University of Tartu,Wellcome Centre for Human Genetics,Kyushu University4 aut |
| 700 | 1 | a Eccles, DAu Medical University of Graz,Queensland University of Technology4 aut |
| 700 | 1 | a Van Eijk, KRu University of Helsinki4 aut |
| 700 | 1 | a Fuchsberger, Cu University of Lübeck4 aut |
| 700 | 1 | a Gao, Hu Imperial College London,Leiden University Medical Center4 aut |
| 700 | 1 | a Germain, Mu QIMR Berghofer Medical Research Institute,Université Paris Cité4 aut |
| 700 | 1 | a Gordon, SDu QIMR Berghofer Medical Research Institute,National Institutes of Health4 aut |
| 700 | 1 | a de Haan, HGu University of Trieste4 aut |
| 700 | 1 | a Harris, SEu Imperial College London,University of Edinburgh,University of Milan4 aut |
| 700 | 1 | a Hofer, Eu Medical University of Graz4 aut |
| 700 | 1 | a Huerta-Chagoya, Au Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán4 aut |
| 700 | 1 | a Igartua, Cu UCLA Medical Center,Harvard University,University of Chicago4 aut |
| 700 | 1 | a Jansen, IEu Vrije Universiteit Amsterdam4 aut |
| 700 | 1 | a Jia, YCu UCLA Medical Center4 aut |
| 700 | 1 | a Kacprowski, Tu Technical University of Munich4 aut |
| 700 | 1 | a Karlsson, Torgnyu Uppsala universitet,Medicinsk genetik och genomik,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)tka28508 |
| 700 | 1 | a Kleber, MEu National Institutes of Health,Karolinska Institutet,Heidelberg University4 aut |
| 700 | 1 | a Li, SAu University of Eastern Finland,Royal College of Surgeons in Ireland,Leidos,Imperial College London4 aut |
| 700 | 1 | a Li-Gao, Ru Leiden University Medical Center4 aut |
| 700 | 1 | a Mahajan, Au University of Edinburgh,Erasmus MC4 aut |
| 700 | 1 | a Matsuda, Ku The University of Tokyo4 aut |
| 700 | 1 | a Meidtner, Ku German Center for Diabetes Research4 aut |
| 700 | 1 | a Meng, Wu Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia,University of Dundee4 aut |
| 700 | 1 | a Montasser, MEu University of Maryland, Baltimore4 aut |
| 700 | 1 | a van der Most, PJu University of Lübeck,National Institutes of Health,University Medical Center Groningen4 aut |
| 700 | 1 | a Munz, Mu University of Edinburgh,Greifswald University Hospital,University Medical Center Groningen,University of Washington,Harvard University,National Institutes of Health4 aut |
| 700 | 1 | a Nutile, Tu Institute of Genetics and Biophysics4 aut |
| 700 | 1 | a Palviainen, Tu University of Vermont,University of Helsinki4 aut |
| 700 | 1 | a Prasad, Gu Institute of Genomics and Integrative Biology4 aut |
| 700 | 1 | a Prasad, Rashmi Bu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-rpa |
| 700 | 1 | a Priyanka, TDSu San Raffaele Research Institute, Milano, Italy,University of Tartu,Leiden University Medical Center,Centre for Cellular and Molecular Biology4 aut |
| 700 | 1 | a Rizzi, Fu University of Milan4 aut |
| 700 | 1 | a Salvi, Eu University of Iceland4 aut |
| 700 | 1 | a Sapkota, BR4 aut |
| 700 | 1 | a Shriner, Du Shahid Beheshti University of Medical Sciences,University of Dundee4 aut |
| 700 | 1 | a Skotte, Lu University of Michigan–Ann Arbor,Statens Serum Institut4 aut |
| 700 | 1 | a Smart, MCu University of Trieste,Helmholtz Zentrum München,Northwestern University,University of Essex4 aut |
| 700 | 1 | a Smith, AVu University of Edinburgh,RMIT University4 aut |
| 700 | 1 | a van der Spek, Au Erasmus MC,National Institutes of Health4 aut |
| 700 | 1 | a Spracklen, CNu University of North Carolina at Chapel Hill4 aut |
| 700 | 1 | a Strawbridge, RJu Karolinska Institutet,University of Glasgow4 aut |
| 700 | 1 | a Tajuddin, SM4 aut |
| 700 | 1 | a Trompet, S4 aut |
| 700 | 1 | a Turman, Cu Harvard University4 aut |
| 700 | 1 | a Verweij, Nu University Medical Center Groningen4 aut |
| 700 | 1 | a Viberti, Cu University of Turin4 aut |
| 700 | 1 | a Wang, Lu Utrecht University,Washington University in St. Louis4 aut |
| 700 | 1 | a Warren, HR4 aut |
| 700 | 1 | a Wootton, REu Greifswald University Hospital,University of Bristol4 aut |
| 700 | 1 | a Yanek, LR4 aut |
| 700 | 1 | a Yao, J4 aut |
| 700 | 1 | a Yousri, NAu Erasmus MC,Alexandria University4 aut |
| 700 | 1 | a Zhao, Wu University of Michigan–Ann Arbor4 aut |
| 700 | 1 | a Adeyemo, AAu University of Newcastle Australia,Population Health Science, Bristol Medical School, Bristol, BS8 2BY, UK,Children's Hospital of Philadelphia,University of Lübeck,University of Groningen,Queensland University of Technology,University of Western Australia,Data Tecnica International,Rush University Medical Center,University of Michigan–Ann Arbor,University of Washington,University of Southern California,Erasmus University Rotterdam,Erasmus MC,Queen Mary University of London,University of Cambridge,University of California, San Diego4 aut |
| 700 | 1 | a Afaq, S4 aut |
| 700 | 1 | a Aguilar-Salinas, CAu University of Edinburgh,Tecnológico de Monterrey4 aut |
| 700 | 1 | a Akiyama, M4 aut |
| 700 | 1 | a Albert, MLu Imperial College London,University of Eastern Finland,University of Tartu,University Hospital Schleswig-Holstein,Department of Cancer Immunology, Genentech Inc, San Francisco, California, 94080, USA4 aut |
| 700 | 1 | a Allison, MA4 aut |
| 700 | 1 | a Alver, M4 aut |
| 700 | 1 | a Aung, Tu National University of Singapore4 aut |
| 700 | 1 | a Azizi, Fu Shahid Beheshti University of Medical Sciences4 aut |
| 700 | 1 | a Bentley, ARu University of Trieste4 aut |
| 700 | 1 | a Boeing, Hu National Institutes of Health,University of Potsdam4 aut |
| 700 | 1 | a Boerwinkle, Eu The University of Texas Health Science Center at Houston4 aut |
| 700 | 1 | a Borja, JBu QIMR Berghofer Medical Research Institute,Capital Medical University,University of San Carlos,Utrecht University4 aut |
| 700 | 1 | a de Borst, GJ4 aut |
| 700 | 1 | a Bottinger, EPu Health Data Research UK,Institut Pasteur,Hasso Plattner Institute4 aut |
| 700 | 1 | a Broer, Lu Erasmus MC4 aut |
| 700 | 1 | a Campbell, Hu University of Edinburgh,Cornell University4 aut |
| 700 | 1 | a Chanock, Su National Institutes of Health4 aut |
| 700 | 1 | a Chee, MLu National University of Singapore4 aut |
| 700 | 1 | a Chen, Gu National Institutes of Health4 aut |
| 700 | 1 | a Chen, YDI4 aut |
| 700 | 1 | a Chen, ZMu University of Oxford4 aut |
| 700 | 1 | a Chiu, YFu Hadassah Medical Center,National Health Research Institutes4 aut |
| 700 | 1 | a Cocca, Mu University of Trieste,The University of Texas Health Science Center at Houston,University of Virginia4 aut |
| 700 | 1 | a Collins, FSu Montreal Heart Institute4 aut |
| 700 | 1 | a Concas, MPu Vita-Salute San Raffaele University,National Academies of Sciences, Engineering, and Medicine,National Institutes of Health4 aut |
| 700 | 1 | a Corley, Ju University of Edinburgh,Imperial College Healthcare NHS Trust4 aut |
| 700 | 1 | a Cugliari, Gu University of Turin4 aut |
| 700 | 1 | a Van Dam, RMu University of Tartu4 aut |
| 700 | 1 | a Damulina, A4 aut |
| 700 | 1 | a Daneshpour, MS4 aut |
| 700 | 1 | a Day, FRu Erasmus MC4 aut |
| 700 | 1 | a Delgado, GEu Heidelberg University4 aut |
| 700 | 1 | a Dhana, Ku UCLA Medical Center,Harvard University,University of Cambridge,University of Split4 aut |
| 700 | 1 | a Doney, ASFu Kiel University4 aut |
| 700 | 1 | a Dorr, Mu Greifswald University Hospital4 aut |
| 700 | 1 | a Doumatey, APu National Institutes of Health,University of Edinburgh4 aut |
| 700 | 1 | a Dzimiri, Nu Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia4 aut |
| 700 | 1 | a Ebenesersdottir, SSu College Station Medical Center,National University of Singapore4 aut |
| 700 | 1 | a Elliott, Ju Imperial College London4 aut |
| 700 | 1 | a Elliott, Pu University of Newcastle Australia4 aut |
| 700 | 1 | a Ewert, R4 aut |
| 700 | 1 | a Felix, JFu Univ Edinburgh, Usher Inst, Ctr Global Hlth Res, Edinburgh, Midlothian, Scotland; Osaka Univ, Dept Stat Genet, Grad Sch Med, Suita, Osaka, Japan; Osaka Univ, Immunol Frontier Res Ctr WPI IFReC, Lab Stat Immunol, Suita, Osaka, Japan; Amgen Inc, DeCODE Genet, Reykjavik, Iceland,University of Edinburgh,Erasmus MC,Icahn School of Medicine at Mount Sinai4 aut |
| 700 | 1 | a Fischer, Ku University of Tartu4 aut |
| 700 | 1 | a Freedman, BIu Wake Forest University4 aut |
| 700 | 1 | a Girotto, Gu Utrecht University,University of Helsinki,Erasmus University Rotterdam,University of Oxford4 aut |
| 700 | 1 | a Goel, Au Wellcome Centre for Human Genetics4 aut |
| 700 | 1 | a Gogele, Mu University of Lübeck4 aut |
| 700 | 1 | a Goodarzi, MOu Cedars-Sinai Medical Center4 aut |
| 700 | 1 | a Graff, Mu University of Queensland,University of North Carolina at Chapel Hill4 aut |
| 700 | 1 | a Granot-Hershkovitz, Eu Hadassah Medical Center4 aut |
| 700 | 1 | a Grodstein, Fu Harvard University4 aut |
| 700 | 1 | a Guarrera, Su University of Turin4 aut |
| 700 | 1 | a Gudbjartsson, DFu University of Iceland4 aut |
| 700 | 1 | a Guity, Ku Shahid Beheshti University of Medical Sciences4 aut |
| 700 | 1 | a Gunnarsson, Bu Amgen4 aut |
| 700 | 1 | a Guo, Yu Chinese Academy of Medical Sciences & Peking Union Medical College4 aut |
| 700 | 1 | a Hagenaars, SPu Amgen,University of Glasgow,University of Edinburgh4 aut |
| 700 | 1 | a Haiman, CA4 aut |
| 700 | 1 | a Halevy, Au Hadassah Medical Center4 aut |
| 700 | 1 | a Harris, TB4 aut |
| 700 | 1 | a Hedayati, Mu Shahid Beheshti University of Medical Sciences4 aut |
| 700 | 1 | a van Heel, DA4 aut |
| 700 | 1 | a Hirata, Mu The University of Tokyo4 aut |
| 700 | 1 | a Hofer, Iu Utrecht University4 aut |
| 700 | 1 | a Hsiung, CAu National Health Research Institutes4 aut |
| 700 | 1 | a Huang, JYu National Defense Medical Center,Rush University Medical Center4 aut |
| 700 | 1 | a Hung, YJ4 aut |
| 700 | 1 | a Ikram, MA4 aut |
| 700 | 1 | a Jagadeesan, Au University Medical Center Groningen,University of Iceland4 aut |
| 700 | 1 | a Jousilahti, Pu University of Edinburgh,Imperial College London4 aut |
| 700 | 1 | a Kamatani, Yu Kyoto University4 aut |
| 700 | 1 | a Kanai, Mu Osaka University4 aut |
| 700 | 1 | a Kerrison, ND4 aut |
| 700 | 1 | a Kessler, Tu Technical University of Munich4 aut |
| 700 | 1 | a Khaw, KTu University of Cambridge4 aut |
| 700 | 1 | a Khor, CC4 aut |
| 700 | 1 | a de Kleijn, DPVu University of Lausanne,Vrije Universiteit Amsterdam,Utrecht University4 aut |
| 700 | 1 | a Koh, WPu Columbia University Irving Medical Center,National University of Singapore4 aut |
| 700 | 1 | a Kolcic, I4 aut |
| 700 | 1 | a Kraft, Pu Harvard University,University of Edinburgh4 aut |
| 700 | 1 | a Kramer, BKu Heidelberg University4 aut |
| 700 | 1 | a Kutalik, Zu SIB Swiss Institute of Bioinformatics4 aut |
| 700 | 1 | a Kuusisto, Ju University of Eastern Finland,Amgen4 aut |
| 700 | 1 | a Langenberg, C4 aut |
| 700 | 1 | a Launer, LJu National Institutes of Health,Agency for Science, Technology and Research,Broad Institute,University of Helsinki,University Medical Center Groningen4 aut |
| 700 | 1 | a Lawlor, DA4 aut |
| 700 | 1 | a Lee, ITu Chung Shan Medical University,Imperial College London4 aut |
| 700 | 1 | a Lee, WJu Taichung Veterans General Hospital,Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, BD96RJ, UK4 aut |
| 700 | 1 | a Lerch, MM4 aut |
| 700 | 1 | a Li, LM4 aut |
| 700 | 1 | a Liu, JJ4 aut |
| 700 | 1 | a Loh, M4 aut |
| 700 | 1 | a London, SJu National Institutes of Health4 aut |
| 700 | 1 | a Loomis, Su Johns Hopkins University4 aut |
| 700 | 1 | a Lu, YCu Mount Sinai Hospital4 aut |
| 700 | 1 | a Luan, Ju University of Cambridge,University of Pittsburgh4 aut |
| 700 | 1 | a Magi, R4 aut |
| 700 | 1 | a Manichaikul, AWu University of Virginia4 aut |
| 700 | 1 | a Manunta, P4 aut |
| 700 | 1 | a Masson, Gu Amgen4 aut |
| 700 | 1 | a Matoba, Nu RIKEN Center for Integrative Medical Sciences4 aut |
| 700 | 1 | a Mei, XWu University of Oxford4 aut |
| 700 | 1 | a Meisinger, C4 aut |
| 700 | 1 | a Meitinger, T4 aut |
| 700 | 1 | a Mezzavilla, M4 aut |
| 700 | 1 | a Milani, L4 aut |
| 700 | 1 | a Millwood, IYu University of Oxford4 aut |
| 700 | 1 | a Momozawa, Yu RIKEN Center for Integrative Medical Sciences4 aut |
| 700 | 1 | a Moore, A4 aut |
| 700 | 1 | a Morange, PEu Aix-Marseille University4 aut |
| 700 | 1 | a Moreno-Macias, Hu Universidad Autónoma Metropolitana4 aut |
| 700 | 1 | a Mori, TAu Karolinska Institutet,Greifswald University Hospital4 aut |
| 700 | 1 | a Morrison, AC4 aut |
| 700 | 1 | a Muka, T4 aut |
| 700 | 1 | a Murakami, Yu The University of Tokyo4 aut |
| 700 | 1 | a Murray, AD4 aut |
| 700 | 1 | a de Mutsert, Ru Leiden University Medical Center4 aut |
| 700 | 1 | a Mychaleckyj, JC4 aut |
| 700 | 1 | a Nalls, MA4 aut |
| 700 | 1 | a Nauck, Mu Greifswald University Hospital4 aut |
| 700 | 1 | a Neville, MJu University of Oxford4 aut |
| 700 | 1 | a Nolte, IM4 aut |
| 700 | 1 | a Ong, KKu University of Cambridge4 aut |
| 700 | 1 | a Orozco, Lu Medicina4 aut |
| 700 | 1 | a Padmanabhan, S4 aut |
| 700 | 1 | a Palsson, G4 aut |
| 700 | 1 | a Pankow, JSu University of Minnesota4 aut |
| 700 | 1 | a Pattaro, Cu University of Lübeck4 aut |
| 700 | 1 | a Pattie, A4 aut |
| 700 | 1 | a Polasek, Ou University of Split4 aut |
| 700 | 1 | a Poulter, Nu Imperial College London4 aut |
| 700 | 1 | a Pramstaller, PPu Children's Hospital of Philadelphia4 aut |
| 700 | 1 | a Quintana-Murci, Lu Institut Pasteur4 aut |
| 700 | 1 | a Raikkonen, K4 aut |
| 700 | 1 | a Ralhan, Su Hero Heart Institute and Dyanand Medical College and Hospital, Ludhiana, Punjab, India4 aut |
| 700 | 1 | a Rao, DCu Washington University in St. Louis,New York University,University of Milan4 aut |
| 700 | 1 | a van Rheenen, Wu University Medical Center Utrecht4 aut |
| 700 | 1 | a Rich, SSu University of Virginia4 aut |
| 700 | 1 | a Ridker, PM4 aut |
| 700 | 1 | a Rietveld, CA4 aut |
| 700 | 1 | a Robino, A4 aut |
| 700 | 1 | a Johansson, Åsau Uppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik4 aut0 (Swepub:uu)asjoh108 |
| 700 | 1 | a Ruggiero, Du Istituto Neurologico Mediterraneo4 aut |
| 700 | 1 | a Saba, Yu Medical University of Graz4 aut |
| 700 | 1 | a Sabanayagam, Cu National University of Singapore4 aut |
| 700 | 1 | a Sabater-Lleal, Mu Karolinska Institutet4 aut |
| 700 | 1 | a Sala, CFu San Raffaele Research Institute, Milano, Italy4 aut |
| 700 | 1 | a Salomaa, Vu National Institutes of Health4 aut |
| 700 | 1 | a Sandow, Ku Imperial College London4 aut |
| 700 | 1 | a Schmidt, H4 aut |
| 700 | 1 | a Scott, LJ4 aut |
| 700 | 1 | a Scott, WR4 aut |
| 700 | 1 | a Sedaghati-Khayat, Bu Shahid Beheshti University of Medical Sciences4 aut |
| 700 | 1 | a Sennblad, Bengtu Uppsala universitet,Molekylär evolution,Science for Life Laboratory, SciLifeLab,Karolinska Inst, Ctr Mol Med, Dept Med Solna, Cardiovasc Med Unit, Stockholm, Sweden,Karolinska Institutet4 aut0 (Swepub:uu)bengtsb |
| 700 | 1 | a van Setten, Ju Utrecht University4 aut |
| 700 | 1 | a Sever, PJ4 aut |
| 700 | 1 | a Sheu, WHHu Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan, Taiwan4 aut |
| 700 | 1 | a Shi, Yu National University of Singapore4 aut |
| 700 | 1 | a Shrestha, Su Dayanand Medical College & Hospital,Children's Hospital of Philadelphia4 aut |
| 700 | 1 | a Shukla, SRu Medical University of Graz,Symbiosis International University4 aut |
| 700 | 1 | a Sigurdsson, JKu University of Helsinki4 aut |
| 700 | 1 | a Sikka, TT4 aut |
| 700 | 1 | a Singh, JRu Panjab University4 aut |
| 700 | 1 | a Smith, BHu University of Dundee4 aut |
| 700 | 1 | a Stancakova, A4 aut |
| 700 | 1 | a Stanton, A4 aut |
| 700 | 1 | a Starr, JM4 aut |
| 700 | 1 | a Stefansdottir, Lu Amgen4 aut |
| 700 | 1 | a Straker, Lu Curtin University4 aut |
| 700 | 1 | a Sulem, P4 aut |
| 700 | 1 | a Sveinbjornsson, Gu Amgen4 aut |
| 700 | 1 | a Swertz, MA4 aut |
| 700 | 1 | a Taylor, AM4 aut |
| 700 | 1 | a Taylor, KD4 aut |
| 700 | 1 | a Terzikhan, Nu Ghent University Hospital4 aut |
| 700 | 1 | a Tham, YCu National University of Singapore4 aut |
| 700 | 1 | a Thorleifsson, Gu Amgen4 aut |
| 700 | 1 | a Thorsteinsdottir, Uu RMIT University4 aut |
| 700 | 1 | a Tillander, A4 aut |
| 700 | 1 | a Tracy, RP4 aut |
| 700 | 1 | a Tusie-Luna, Tu Universidad Nacional Autónoma de México4 aut |
| 700 | 1 | a Tzoulaki, I4 aut |
| 700 | 1 | a Vaccargiu, Su National Academies of Sciences, Engineering, and Medicine4 aut |
| 700 | 1 | a Vangipurapu, Ju Erasmus MC,University of Eastern Finland4 aut |
| 700 | 1 | a Veldink, JHu University Medical Center Utrecht4 aut |
| 700 | 1 | a Vitart, V4 aut |
| 700 | 1 | a Volker, Uu Greifswald University Hospital4 aut |
| 700 | 1 | a Vuoksimaa, Eu University of Helsinki4 aut |
| 700 | 1 | a Wakil, SM4 aut |
| 700 | 1 | a Waldenberger, Mu Helmholtz Zentrum München4 aut |
| 700 | 1 | a Wander, GS4 aut |
| 700 | 1 | a Wang, YXu Capital Medical University4 aut |
| 700 | 1 | a Wareham, NJu University of Cambridge4 aut |
| 700 | 1 | a Wild, Su University of Edinburgh4 aut |
| 700 | 1 | a Yajnik, CSu Hadassah Medical Center4 aut |
| 700 | 1 | a Yuan, JM4 aut |
| 700 | 1 | a Zeng, LYu Technical University of Munich,Rush University Medical Center4 aut |
| 700 | 1 | a Zhang, L4 aut |
| 700 | 1 | a Zhou, Ju National Institutes of Health4 aut |
| 700 | 1 | a Amin, N4 aut |
| 700 | 1 | a Asselbergs, FWu Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK4 aut |
| 700 | 1 | a Bakker, SJL4 aut |
| 700 | 1 | a Becker, DM4 aut |
| 700 | 1 | a Lehne, Bu Imperial College London4 aut |
| 700 | 1 | a Bennett, DA4 aut |
| 700 | 1 | a den Berg, LHu University Medical Center Utrecht4 aut |
| 700 | 1 | a Berndt, SIu National Institutes of Health4 aut |
| 700 | 1 | a Bharadwaj, Du Jawaharlal Nehru University4 aut |
| 700 | 1 | a Bielak, LFu University of Michigan–Ann Arbor,University of Groningen4 aut |
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| 700 | 1 | a Smith, GDu University of Bristol4 aut |
| 700 | 1 | a Deary, IJu University of Edinburgh4 aut |
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| 700 | 1 | a Franke, A4 aut |
| 700 | 1 | a Friedlander, Y4 aut |
| 700 | 1 | a Gasparini, Pu University of Trieste4 aut |
| 700 | 1 | a Gieger, Cu German Center for Diabetes Research4 aut |
| 700 | 1 | a Gonzalez, Cu Instituto Nacional de Salud Pública4 aut |
| 700 | 1 | a Goyette, Pu Montreal Heart Institute4 aut |
| 700 | 1 | a Grant, SFA4 aut |
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| 700 | 1 | a Groop, Leifu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital,Institute for Molecular Medicine Finland (FIMM),University of Helsinki4 aut0 (Swepub:lu)endo-lgr |
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| 700 | 1 | a Hamsten, Au Karolinska Institutet,Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76, Sweden4 aut |
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| 700 | 1 | a Heng, CKu National University of Singapore4 aut |
| 700 | 1 | a Hicks, AA4 aut |
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| 700 | 1 | a Johannesson, Mu University of Otago4 aut |
| 700 | 1 | a Johansson, A4 aut |
| 700 | 1 | a Jonas, JB4 aut |
| 700 | 1 | a Jukema, JWu Leiden University Medical Center4 aut |
| 700 | 1 | a Junttila, Ju University of Bristol4 aut |
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| 700 | 1 | a Karpe, Fu University of Oxford4 aut |
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| 700 | 1 | a Ober, Cu University of Chicago4 aut |
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| 700 | 1 | a Palmas, W4 aut |
| 700 | 1 | a Palmer, Cu University of Dundee4 aut |
| 700 | 1 | a Pasterkamp, GG4 aut |
| 700 | 1 | a Patin, E4 aut |
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| 710 | 2 | a Univ Edinburgh, Usher Inst, Ctr Global Hlth Res, Edinburgh, Midlothian, Scotlandb University of Edinburgh4 org |
| 710 | 2 | a et al. |
| 773 | 0 | t Nature communicationsd : Springer Science and Business Media LLCg 10:1, s. 4957-q 10:1<4957-x 2041-1723 |
| 856 | 4 | u https://www.nature.com/articles/s41467-019-12283-6.pdf |
| 856 | 4 | u https://doi.org/10.1038/s41467-019-12283-6y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1371639/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u http://dx.doi.org/10.1038/s41467-019-12283-6x freey FULLTEXT |
| 856 | 4 | u https://research.hhs.se/esploro/outputs/journalArticle/Associations-of-autozygosity-with-a-broad/991001506399506056x primaryx Object in context |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:142198309 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-019-12283-6 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397418 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/673d0f2c-31e3-4a1d-8590-c463e479d317 |
| 856 | 4 8 | u https://research.hhs.se/esploro/outputs/journalArticle/Associations-of-autozygosity-with-a-broad/991001506399506056 |
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