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Crosstalk between R...
Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma
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- Karvonen, H (author)
- University of Tampere
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- Chiron, D (author)
- University of Nantes,Nantes University Hospital
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- Niininen, W (author)
- University of Tampere
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- Ek, Sara (author)
- Lund University,Lunds universitet,Institutionen för immunteknologi,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Immunotechnology,Departments at LTH,Faculty of Engineering, LTH
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- Jerkeman, Mats (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Moradi, E (author)
- University of Tampere
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- Nykter, M (author)
- University of Tampere
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- Heckman, CA (author)
- University of Helsinki
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- Kallioniemi, O (author)
- Karolinska Institutet,University of Helsinki
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- Murumagi, A (author)
- University of Helsinki
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- Ungureanu, D (author)
- University of Tampere
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(creator_code:org_t)
- 2017-11-09
- 2017
- English.
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In: Blood advances. - : American Society of Hematology. - 2473-9529 .- 2473-9537. ; 1:24, s. 2257-2268
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Abstract
Subject headings
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- Targeting ROR1 downregulates NF-κB p65 expression and sensitizes MCL cells to BCR- or Bcl-2–targeted drugs. Inhibition of BCR signaling by BTK-specific inhibitors such as ibrutinib impairs ROR1 levels and consecutively ROR1-targeted therapies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Karvonen, H
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Chiron, D
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Niininen, W
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Ek, Sara
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Jerkeman, Mats
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Moradi, E
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show more...
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Nykter, M
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Heckman, CA
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Kallioniemi, O
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Murumagi, A
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Ungureanu, D
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Blood advances
- By the university
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Karolinska Institutet
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Lund University