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The age of randomiz...
The age of randomized clinical trials: three important aspects of randomized clinical trials in cardiovascular pharmacotherapy with examples from lipid and diabetes trials
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Drexel, H (author)
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Rosano, GMC (author)
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Lewis, BS (author)
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Huber, K (author)
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Vonbank, A (author)
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Dopheide, JF (author)
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Mader, A (author)
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Niessner, A (author)
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- Savarese, G (author)
- Karolinska Institutet
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Wassmann, S (author)
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- Agewall, S (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2019-08-29
- 2020
- English.
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In: European heart journal. Cardiovascular pharmacotherapy. - : Oxford University Press (OUP). - 2055-6845 .- 2055-6837. ; 6:2, s. 97-103
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https://doi.org/10.1...
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Abstract
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- Randomized clinical trials (RCTs) are important and the Gold Standard for drugs in modern cardiovascular (CV) therapy. The cornerstone of RCTs is the recording of hard clinical endpoints instead of surrogates. It is important to select an appropriate endpoint. Efficacy endpoints must be clinically relevant and can be hierarchically divided. A very interesting innovation in endpoint acquisition is the total event paradigm.
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Drexel, H
-
Rosano, GMC
-
Lewis, BS
-
Huber, K
-
Vonbank, A
-
Dopheide, JF
-
show more...
-
Mader, A
-
Niessner, A
-
Savarese, G
-
Wassmann, S
-
Agewall, S
-
show less...
- Articles in the publication
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European heart j ...
- By the university
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Karolinska Institutet