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Functional annotati...
Functional annotation of human long noncoding RNAs via molecular phenotyping
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Ramilowski, JA (author)
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Yip, CW (author)
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Agrawal, S (author)
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show more...
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Chang, JC (author)
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Ciani, Y (author)
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Kulakovskiy, IV (author)
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Mendez, M (author)
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Ooi, JL (author)
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Ouyang, JF (author)
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Parkinson, N (author)
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Petri, A (author)
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Roos, L (author)
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Severin, J (author)
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Yasuzawa, K (author)
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Abugessaisa, I (author)
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Akalin, A (author)
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Antonov, IV (author)
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Arner, E (author)
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Bonetti, A (author)
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Bono, H (author)
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Borsari, B (author)
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Brombacher, F (author)
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Cameron, CJF (author)
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Cannistraci, CV (author)
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Cardenas, R (author)
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Cardon, M (author)
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Chang, HW (author)
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Dostie, J (author)
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Ducoli, L (author)
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Favorov, A (author)
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Fort, A (author)
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Garrido, D (author)
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Gil, N (author)
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Gimenez, J (author)
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Guler, R (author)
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Handoko, L (author)
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Harshbarger, J (author)
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Hasegawa, A (author)
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Hasegawa, Y (author)
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Hashimoto, K (author)
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Hayatsu, N (author)
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Heutink, P (author)
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Hirose, T (author)
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Imada, EL (author)
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Itoh, M (author)
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Kaczkowski, B (author)
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Kanhere, A (author)
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Kawabata, E (author)
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Kawaji, H (author)
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Kawashima, T (author)
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Kelly, ST (author)
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Kojima, M (author)
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Kondo, N (author)
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Koseki, H (author)
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Kouno, T (author)
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Kratz, A (author)
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Kurowska-Stolarska, M (author)
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Kwon, ATJ (author)
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Leek, J (author)
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- Lennartsson, A (author)
- Karolinska Institutet
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Lizio, M (author)
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Lopez-Redondo, F (author)
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Luginbuhl, J (author)
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Maeda, S (author)
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Makeev, VJ (author)
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Marchionni, L (author)
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Medvedeva, YA (author)
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Minoda, A (author)
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Muller, F (author)
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Munoz-Aguirre, M (author)
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Murata, M (author)
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Nishiyori, H (author)
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Nitta, KR (author)
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Noguchi, S (author)
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Noro, Y (author)
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Nurtdinov, R (author)
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Okazaki, Y (author)
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Orlando, V (author)
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Paquette, D (author)
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Parr, CJC (author)
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Rackham, OJL (author)
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Rizzu, P (author)
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Martinez, DFS (author)
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Sandelin, A (author)
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Sanjana, P (author)
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Semple, CAM (author)
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Shibayama, Y (author)
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Sivaraman, DM (author)
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Suzuki, T (author)
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Szumowski, SC (author)
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Tagami, M (author)
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Taylor, MS (author)
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Terao, C (author)
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Thodberg, M (author)
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Thongjuea, S (author)
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Tripathi, V (author)
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Ulitsky, I (author)
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Verardo, R (author)
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Vorontsov, IE (author)
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Yamamoto, C (author)
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Young, RS (author)
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Baillie, JK (author)
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Forrest, ARR (author)
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Guigo, R (author)
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Hoffman, MM (author)
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Hon, CC (author)
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Kasukawa, T (author)
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Kauppinen, S (author)
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- Kere, J (author)
- Karolinska Institutet
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Lenhard, B (author)
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Schneider, C (author)
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Suzuki, H (author)
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Yagi, K (author)
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de Hoon, MJL (author)
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Shin, JW (author)
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Carninci, P (author)
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(creator_code:org_t)
- 2020-07-27
- 2020
- English.
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In: Genome research. - : Cold Spring Harbor Laboratory. - 1549-5469 .- 1088-9051. ; 30:7, s. 1060-1072
- Related links:
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https://genome.cshlp...
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http://kipublication...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression of 285 lncRNAs in human dermal fibroblasts and quantified cellular growth, morphological changes, and transcriptomic responses using Capped Analysis of Gene Expression (CAGE). Antisense oligonucleotides targeting the same lncRNAs exhibited global concordance, and the molecular phenotype, measured by CAGE, recapitulated the observed cellular phenotypes while providing additional insights on the affected genes and pathways. Here, we disseminate the largest-to-date lncRNA knockdown data set with molecular phenotyping (over 1000 CAGE deep-sequencing libraries) for further exploration and highlight functional roles for ZNF213-AS1 and lnc-KHDC3L-2.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
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Ramilowski, JA
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Yip, CW
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Agrawal, S
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Chang, JC
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Ciani, Y
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Kulakovskiy, IV
-
show more...
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Mendez, M
-
Ooi, JL
-
Ouyang, JF
-
Parkinson, N
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Petri, A
-
Roos, L
-
Severin, J
-
Yasuzawa, K
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Abugessaisa, I
-
Akalin, A
-
Antonov, IV
-
Arner, E
-
Bonetti, A
-
Bono, H
-
Borsari, B
-
Brombacher, F
-
Cameron, CJF
-
Cannistraci, CV
-
Cardenas, R
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Cardon, M
-
Chang, HW
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Dostie, J
-
Ducoli, L
-
Favorov, A
-
Fort, A
-
Garrido, D
-
Gil, N
-
Gimenez, J
-
Guler, R
-
Handoko, L
-
Harshbarger, J
-
Hasegawa, A
-
Hasegawa, Y
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Hashimoto, K
-
Hayatsu, N
-
Heutink, P
-
Hirose, T
-
Imada, EL
-
Itoh, M
-
Kaczkowski, B
-
Kanhere, A
-
Kawabata, E
-
Kawaji, H
-
Kawashima, T
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Kelly, ST
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Kojima, M
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Kondo, N
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Koseki, H
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Kouno, T
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Kratz, A
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Kurowska-Stolars ...
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Kwon, ATJ
-
Leek, J
-
Lennartsson, A
-
Lizio, M
-
Lopez-Redondo, F
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Luginbuhl, J
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Maeda, S
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Makeev, VJ
-
Marchionni, L
-
Medvedeva, YA
-
Minoda, A
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Muller, F
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Munoz-Aguirre, M
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Murata, M
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Nishiyori, H
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Nitta, KR
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Noguchi, S
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Noro, Y
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Nurtdinov, R
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Okazaki, Y
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Orlando, V
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Paquette, D
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Parr, CJC
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Rackham, OJL
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Rizzu, P
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Martinez, DFS
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Sandelin, A
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Sanjana, P
-
Semple, CAM
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Shibayama, Y
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Sivaraman, DM
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Suzuki, T
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Szumowski, SC
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Tagami, M
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Taylor, MS
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Terao, C
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Thodberg, M
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Thongjuea, S
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Tripathi, V
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Ulitsky, I
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Verardo, R
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Vorontsov, IE
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Yamamoto, C
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Young, RS
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Baillie, JK
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Forrest, ARR
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Guigo, R
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Hoffman, MM
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Hon, CC
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Kasukawa, T
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Kauppinen, S
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Kere, J
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Lenhard, B
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Schneider, C
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Suzuki, H
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Yagi, K
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de Hoon, MJL
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Shin, JW
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Carninci, P
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show less...
- Articles in the publication
-
Genome research
- By the university
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Karolinska Institutet