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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003485naa a2200769 4500
001oai:prod.swepub.kib.ki.se:144511803
003SwePub
008240701s2020 | |||||||||||000 ||eng|
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1445118032 URI
024a https://doi.org/10.1038/s41598-020-58746-52 DOI
040 a (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Belmans, N4 aut
2451 0a Quantification of DNA Double Strand Breaks and Oxidation Response in Children and Adults Undergoing Dental CBCT Scan
264 c 2020-02-07
264 1b Springer Science and Business Media LLC,c 2020
520 a Assessing the possible biological effects of exposure to low doses of ionizing radiation (IR) is one of the prime challenges in radiation protection, especially in medical imaging. Today, radiobiological data on cone beam CT (CBCT) related biological effects are scarce. In children and adults, the induction of DNA double strand breaks (DSBs) in buccal mucosa cells and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) and antioxidant capacity in saliva samples after CBCT examination were examined. No DNA DSBs induction was observed in children nor adults. In children only, an increase in 8-oxo-dG levels was observed 30 minutes after CBCT. At the same time an increase in antioxidant capacity was observed in children, whereas a decrease was observed in adults. Our data indicate that children and adults react differently to IR doses associated with CBCT. Fully understanding these differences could lead to an optimal use of CBCT in different age categories as well as improved radiation protection guidelines.
700a Gilles, L4 aut
700a Vermeesen, R4 aut
700a Virag, P4 aut
700a Hedesiu, M4 aut
700a Salmon, B4 aut
700a Baatout, S4 aut
700a Lucas, S4 aut
700a Lambrichts, I4 aut
700a Jacobs, Ru Karolinska Institutet4 aut
700a Moreels, M4 aut
700a Oenning, AC4 aut
700a Chaussain, C4 aut
700a Lefevre, C4 aut
700a Baciut, M4 aut
700a Marcu, M4 aut
700a Almasan, O4 aut
700a Roman, R4 aut
700a Barbur, I4 aut
700a Dinu, C4 aut
700a Rotaru, H4 aut
700a Hurubeanu, L4 aut
700a Istouan, V4 aut
700a Lucaciu, O4 aut
700a Leucuta, D4 aut
700a Crisan, B4 aut
700a Bogdan, L4 aut
700a Candea, C4 aut
700a Bran, S4 aut
700a Baciut, G4 aut
700a Bosmans, H4 aut
700a Bogaerts, R4 aut
700a Politis, C4 aut
700a Stratis, A4 aut
700a Pauwels, R4 aut
700a Vasconcelos, KD4 aut
700a Nicolielo, L4 aut
700a Zhang, G4 aut
700a Tijskens, E4 aut
700a Vranckx, M4 aut
700a Ockerman, A4 aut
700a Claerhout, E4 aut
700a Embrechts, E4 aut
710a Karolinska Institutet4 org
773t Scientific reportsd : Springer Science and Business Media LLCg 10:1, s. 2113-q 10:1<2113-x 2045-2322
856u https://www.nature.com/articles/s41598-020-58746-5.pdf
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:144511803
8564 8u https://doi.org/10.1038/s41598-020-58746-5

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