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Patients in complet...
Patients in complete remission after R-CHOP(-like) therapy for diffuse large B-cell lymphoma have limited excess use of health care services in Denmark
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- Jakobsen, LH (author)
- Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark.;Aalborg Univ, Dept Clin Med, Aalborg, Denmark.
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- Ovlisen, AK (author)
- Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark.;Aalborg Univ, Dept Clin Med, Aalborg, Denmark.
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- Severinsen, MT (author)
- Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark.;Aalborg Univ, Dept Clin Med, Aalborg, Denmark.
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- Baech, J (author)
- Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark.
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- Kragholm, KH (author)
- Aalborg Univ Hosp, Unit Clin Biostat & Epidemiol, Aalborg, Denmark.;Aalborg Univ Hosp, Dept Cardiol, Aalborg, Denmark.
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- Glimelius, Ingrid, 1975- (author)
- Uppsala universitet,Karolinska Institutet,Experimentell och klinisk onkologi,Science for Life Laboratory, SciLifeLab,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.
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- Gang, AO (author)
- Rigshosp, Dept Hematol, Copenhagen, Denmark.
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- Jorgensen, JM (author)
- Aarhus Univ Hosp, Dept Hematol, Aarhus, Denmark.
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- Frederiksen, H (author)
- Odense Univ Hosp, Dept Hematol, Odense, Denmark.
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- Poulsen, CB (author)
- Zealand Univ Hosp, Dept Hematol, Roskilde, Denmark.
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- Clausen, MR (author)
- Vejle Sygehus, Dept Hematol, Vejle, Denmark.
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- Pedersen, PT (author)
- Sydvestjysk Sygehus, Dept Hematol, Esbjerg, Denmark.,Nordsjaellands Hosp, Dept Cardiol, Hillerod, Denmark.;Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark.
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- Pedersen, RS (author)
- Holstebro Sygehus, Dept Med, Holstebro, Denmark.
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Torp-Pedersen, C (author)
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- Eloranta, S (author)
- Karolinska Institutet,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.
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- El-Galaly, TC (author)
- Karolinska Institutet,Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark.;Aalborg Univ, Dept Clin Med, Aalborg, Denmark.
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Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark;Aalborg Univ, Dept Clin Med, Aalborg, Denmark. Aalborg Univ Hosp, Clin Canc Res Ctr, Dept Hematol, Aalborg, Denmark. (creator_code:org_t)
- 2022-01-27
- 2022
- English.
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In: Blood cancer journal. - : Springer Science and Business Media LLC. - 2044-5385. ; 12:1, s. 16-
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https://uu.diva-port... (primary) (Raw object)
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Abstract
Subject headings
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- For most patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL), R-CHOP immunochemotherapy leads to complete remission and 60–70% of patients remain progression-free after 5 years. Given a median age of 65, it is relevant to disentangle how DLBCL and DLBCL therapy influence health care use among the survivors. In this nationwide study, the health care use among Danish DLBCL patients diagnosed in 2007–2015, who achieved complete remission after R-CHOP(-like) therapy, was explored and compared to matched comparators from the Danish general population. The post-remission 5-year risk of hospitalization was significantly higher among DLBCL survivors (55%) compared to matched comparators (49%, P < 0.001). DLBCL survivors had on average 10.3 (9.3–11.3) inpatient bed days within 5 years of response evaluation, whereas matched comparators had 8.4 (7.9–8.8). The rate of outpatient visits was also significantly higher(excluding routine follow-up visits, incidence rate ratio, 1.3, P < 0.001), but translated into only a very small absolute difference of <1 outpatient visits within 5 years between DLBCL survivors (4.2 visits, 95% CI, 4.0–4.4) and matched comparators (3.8 visits, 95% CI, 3.7–3.9). In conclusion, DLBCL survivors have an increased incidence of hospital visits due to a wide range of conditions, but in absolute terms the excess use of health care services in DLBCL survivors was small.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Jakobsen, LH
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Ovlisen, AK
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Severinsen, MT
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Baech, J
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Kragholm, KH
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Glimelius, Ingri ...
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show more...
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Gang, AO
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Jorgensen, JM
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Frederiksen, H
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Poulsen, CB
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Clausen, MR
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Pedersen, PT
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Pedersen, RS
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Torp-Pedersen, C
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Eloranta, S
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El-Galaly, TC
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Hematology
- Articles in the publication
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Blood cancer jou ...
- By the university
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Karolinska Institutet
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Uppsala University