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Inhaled silica nano...
Inhaled silica nanoparticles cause chronic kidney disease in rats
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Sasai, F (author)
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Rogers, KL (author)
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Orlicky, DJ (author)
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Stem, A (author)
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Schaeffer, J (author)
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Garcia, G (author)
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Fox, J (author)
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Ray, MS (author)
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Butler-Dawson, J (author)
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Gonzalez-Quiroz, M (author)
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Leiva, R (author)
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Taduri, G (author)
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Anutrakululchai, S (author)
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Venugopal, V (author)
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Madero, M (author)
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Glaser, J (author)
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- Wijkstrom, J (author)
- Karolinska Institutet
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- Wernerson, A (author)
- Karolinska Institutet
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Brown, JM (author)
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Johnson, RJ (author)
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Roncal-Jimenez, CA (author)
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(creator_code:org_t)
- American Physiological Society, 2022
- 2022
- English.
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In: American journal of physiology. Renal physiology. - : American Physiological Society. - 1522-1466 .- 1931-857X. ; 323:1, s. F48-F58
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https://doi.org/10.1...
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Abstract
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- Inhalation of silica nanoparticles (SiNPs) released during the burning of sugarcane has been postulated to have a role in chronic kidney disease of unknown etiology (CKDu). We administered 200- and 300-nm amorphous SiNPs to rats by aspiration and observed kidney damage with tubular injury and inflammation that persisted even after stopping the SiNP exposure. These findings support the hypothesis that human exposure to SiNPs found in sugarcane ash could have a participatory role CKDu.
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Sasai, F
-
Rogers, KL
-
Orlicky, DJ
-
Stem, A
-
Schaeffer, J
-
Garcia, G
-
show more...
-
Fox, J
-
Ray, MS
-
Butler-Dawson, J
-
Gonzalez-Quiroz, ...
-
Leiva, R
-
Taduri, G
-
Anutrakululchai, ...
-
Venugopal, V
-
Madero, M
-
Glaser, J
-
Wijkstrom, J
-
Wernerson, A
-
Brown, JM
-
Johnson, RJ
-
Roncal-Jimenez, ...
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show less...
- Articles in the publication
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American journal ...
- By the university
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Karolinska Institutet