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High levels of inte...
High levels of interferon gamma in the plasma of children with complete interferon gamma receptor deficiency
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Fieschi, C (author)
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Dupuis, S (author)
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Picard, C (author)
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- Smith, CIE (author)
- Karolinska Institutet
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Holland, SM (author)
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Casanova, JL (author)
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(creator_code:org_t)
- 2001-04-01
- 2001
- English.
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In: Pediatrics. - : American Academy of Pediatrics (AAP). - 1098-4275 .- 0031-4005. ; 107:4, s. art. no.-e48
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http://kipublication...
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https://doi.org/10.1...
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Abstract
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- We have found that children with complete interferon gamma (IFNγ) receptor deficiency, unlike patients with other genetic defects predisposing them to mycobacterial diseases, have very high levels of IFNγ in their plasma. This unexpected observation provides a simple and accurate diagnostic method for complete IFNγ receptor deficiency in children with clinical disease caused by bacille Calmette-Guérin vaccines or environmental nontuberculous mycobacteria.
Publication and Content Type
- ref (subject category)
- art (subject category)
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Pediatrics
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